Results 71 to 80 of about 19,931 (245)

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

open access: yesiMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu   +7 more
wiley   +1 more source

Analysis of individualized brain–gut association networks and transcriptional patterns in major depressive disorder

open access: yesInterdisciplinary Medicine, EarlyView.
Individualized brain–gut association networks suggest potential neuropathological mechanisms in MDD and MDDSI. Multilevel brain–gut association changes involving HSV‐1 and inflammation may be relevant to MDD, whereas alterations related to insulin metabolism may play a potential role in the neuropathological mechanisms of MDDSI.
Wei Wang   +10 more
wiley   +1 more source

An Efficient Extension of Network Simplex Algorithm [PDF]

open access: yesJournal of Optimization in Industrial Engineering, 2010
In this paper, an efficient extension of network simplex algorithm is presented. In static scheduling problem, where there is no change in situation, the challenge is that the large problems can be solved in a short time.
Hassan Rashidi, Edward P.K Tsang
doaj  

HPV‐6 Positive Eruptive Verruca Vulgaris After Upadacitinib Initiation for Severe Atopic Dermatitis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Oral JAK‐1 inhibitors for atopic dermatitis (AD) are associated with an increased risk of cutaneous viral infections, particularly herpes zoster. Emerging case reports further suggest a link to eruptive human papillomavirus (HPV) disease. A 23‐year‐old transgender man (female‐to‐male) with severe AD developed a rapidly disseminating eruption ...
Mohammed Shanshal   +2 more
wiley   +1 more source

Mapping landowners' willingness to allow recreational deer harvest on their property for managing chronic wasting disease

open access: yesThe Journal of Wildlife Management, EarlyView.
We demonstrate an approach for mapping the probability of landowners' willingness to allow wildlife management actions on their property using chronic wasting disease as a case study. Larger property sizes were associated with higher landowner willingness. We mapped predictions across the contiguous United States at the census tract level.
Eric C. Palm   +3 more
wiley   +1 more source

Investigating Mixed‐Integer Programming Approaches for the p$$ p $$‐α$$ \alpha $$‐Closest‐Center Problem

open access: yesNetworks, EarlyView.
ABSTRACT In this work, we introduce and study the p$$ p $$‐α$$ \alpha $$‐closest‐center problem (pα$$ p\alpha $$CCP), which is a generalization of the p$$ p $$‐second‐center problem, a recently emerged variant of the classical (discrete) p‐center problem.
Elisabeth Gaar   +2 more
wiley   +1 more source

On the Complexity of the Paper Selection Problem for the Italian Research Quality Evaluation (VQR)

open access: yesNetworks, EarlyView.
ABSTRACT This work addresses the paper selection problem that each Italian university and department faced in the context of the research quality evaluation (VQR) of the Italian university system for the period 2020–2024. Given the set of researchers of a university and their associated papers, the problem consists of selecting a fixed number of ...
Francesco Carrabs   +2 more
wiley   +1 more source

Robust simplex algorithm for online optimization

open access: yesPhysical Review Accelerators and Beams, 2018
A new optimization algorithm is introduced for online optimization applications. The algorithm was modified from the popular Nelder-Mead simplex method to make it noise aware and noise resistant.
Xiaobiao Huang
doaj   +1 more source

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