Results 51 to 60 of about 1,130,308 (277)

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

The Role of the Government in the Abdication Crisis of 1936 [PDF]

, 2015
The death of King George V on 20 January 1936 propelled the British nation into a tumultuous predicament that would threaten the stability of the monarchy and its adherence to tradition. When King Edward VIII ascended the throne, his differences from his
Lescault, Meghan C
core   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Mobile Wind Lidar measurements of the spatial variability of atmospheric boundary layer flows in complex terrain [PDF]

EPJ Web of Conferences
Making observations of the spatial structure of atmospheric boundary layer flows is an ongoing challenge that we attempt to address with the development of the surface-based mobile observing platform UWOW (University of Virginia Wind Observatory on ...
De Wekker Stephan F.J., Greco S., Emmitt G.D.   +2 more
doaj   +1 more source

Simpson's Paradox: Examples.

Shanghai archives of psychiatry, 2018
Simpson's paradox is very prevalent in many areas. It characterizes the inconsistency between the conditional and marginal interpretations of the data. In this paper, we illustrate through some examples how the Simpson's paradox can happen in continuous, categorical, and time-to-event data.
WANG, Bokai, WU, Pan, KWAN, Brian, TU, Xin M., FENG, Changyong   +4 more
openaire   +2 more sources

Mrs Simpson's knickers [PDF]

BMJ, 1996
“Was the Duchess of Windsor a man?” shouted the newspaper placards earlier this year after publication of The Duchess of Windsor by Michael Bloch (Weidenfeld and Nicholson, £18.19). The book makes two main assertions: that the duchess, though married three times, never had normal full sexual relations with any of her husbands or lovers and “may have ...
openaire   +2 more sources

...Sexual Relations with that Woman... : Why the Lee Quote is Still Valid [PDF]

, 2011
A quick reflection this week. This started as a comment on Brooks Simpson\u27s comments on Colin Woodward\u27s blog post at his new blog civilwarhistorian highlighting a quote he found in a Massachusetts newspaper. Whew...
Rudy, John M.
core   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Tugas Pedagogis Gembala Dalam Menyiapkan Warga Gereja Menghadapi Perubahan Sosial

Evangelikal: Jurnal Teologi Injili dan Pembinaan Warga Jemaat, 2020
Social change is an inevitable conversation. Everyone needs to be prepared for social change. Likewise for church members, they need to be prepared for social change and there must be a pastoral pedagogical task in preparing church people for social ...
Lenda Dabora J.F. Sagala
doaj   +1 more source