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Road safety evaluation with multiple treatments: A comparison of methods based on simulations
Accident Analysis & Prevention, 2023This paper focuses on ex-post road safety evaluation with multiple treatments. The potential outcome framework for causal inference is introduced to formalize the causal estimands of interest. Various estimation methods are compared via performing simulation experiments based on semi-synthetic data constructed from a London 20 mph zones dataset.
Yingheng Zhang, Haojie Li, Gang Ren
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Research Synthesis Methods, 2023
AbstractSimulated treatment comparison (STC) is an established method for performing population adjustment for the indirect comparison of two treatments, where individual patient data (IPD) are available for one trial but only aggregate level information is available for the other. The most commonly used method is what we call ‘standard STC’.
Landan Zhang +2 more
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AbstractSimulated treatment comparison (STC) is an established method for performing population adjustment for the indirect comparison of two treatments, where individual patient data (IPD) are available for one trial but only aggregate level information is available for the other. The most commonly used method is what we call ‘standard STC’.
Landan Zhang +2 more
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Journal of Clinical Oncology, 2020
e20523 Background: Comparing the effectiveness of multiple myeloma treatments presents a challenge due to the limited number of head-to-head trials with which to conduct indirect treatment comparisons. This is particularly true when subgroup analysis is of interest.
Eric Mackay +6 more
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e20523 Background: Comparing the effectiveness of multiple myeloma treatments presents a challenge due to the limited number of head-to-head trials with which to conduct indirect treatment comparisons. This is particularly true when subgroup analysis is of interest.
Eric Mackay +6 more
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Simulation and Matching-Based Approaches for Indirect Comparison of Treatments
PharmacoEconomics, 2015Estimates of the relative effects of competing treatments are rarely available from head-to-head trials. These effects must therefore be derived from indirect comparisons of results from different studies. The feasibility of comparisons relies on the network linking treatments through common comparators; the reliability of these may also be impacted ...
K Jack, Ishak +2 more
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Comparison of simulated annealing algorithms for conformal therapy treatment planning
International Journal of Radiation Oncology*Biology*Physics, 1995The efficiency of four fast simulated annealing algorithms for optimizing conformal radiation therapy treatment plans was studied and the resulting plans were compared with each other and to optimized conventional plans.Four algorithms were selected on the basis of their reported successes in solving other minimization problems: fast simulated ...
I I, Rosen +4 more
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A Comparison of Numerical Integration Methods and Discontinuity Treatment for EMT Simulations
2018 Power Systems Computation Conference (PSCC), 2018A variety of numerical integration methods are currently being used for simulating electromagnetic transients in commercial software and experimental codes. This paper intends to provide a review and comparison of these methods for time-domain integration, including 2S-DIRK, ARTEMiS art5 solver, and a semi-analytical matrix exponential-based method ...
Xiaopeng Fu +4 more
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