Results 41 to 50 of about 421,397 (304)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A Hybrid Graph Hydrodynamic Method for Modelling Multiple Pipe Failure in Stormwater Networks

Engineering Proceedings
Modelling multiple pipe failure scenarios in stormwater networks is a challenging task due to the computational burden of conventional methods. In this context, this study proposes a hybrid graph hydrodynamic model (GHM) that combines the advantages of ...
Aun Dastgir, Rahul Satish, Mohsen Hajibabaei, Martin Oberascher, Robert Sitzenfrei   +4 more
doaj   +1 more source

Recent results from LHCb for astroparticle physics

SciPost Physics Proceedings, 2023
The LHCb experiment is a general-purpose forward spectrometer designed for the study of heavy flavour physics at the LHC. The acceptance in the pseudorapidity range $2 < \eta < 5$ with full tracking and particle identification capabilities down to very ...
Hans Dembinski on behalf of the LHCb collaboration
doaj   +1 more source

Modeling, simulation, and identification of the servo pumps

IOP Conference Series: Earth and Environmental Science, 2010
This paper contains the results of a systematic research on the steady-state behavior, and the transients occurring in a basic hydrostatic system containing a servo pump. The optimum structure of such a device working in given condition is found step by step, the synthesis stages are alternating with the analysis ones, in order to establish some ...
C G Negoita, D Vasiliu, Ne Vasiliu, C Calinoiu   +3 more
openaire   +1 more source

Hybrid Modeling and Identification of Dynamic Yaw Simulator

Proceedings of the 13th International Conference on Informatics in Control, Automation and Robotics, 2016
The objective of this work is the study and execution of a dynamic model reproducing the dynamics of a road vehicle to implement it in a vehicle simulator. To do this we will use a generic approach using Matlab to model different phenomenons related to the vehicle. In this research, we have taken into account all relevant parameters in vehicle
Noura Achour, Hocine Imine, Lotfi Mederreg, Abdelhafid Allad   +3 more
openaire   +1 more source

Simultaneous identification of models and parameters of scientific simulators

, 2023
Many scientific models are composed of multiple discrete components, and scientists often make heuristic decisions about which components to include. Bayesian inference provides a mathematical framework for systematically selecting model components, but defining prior distributions over model components and developing associated inference schemes has ...
Schröder, Cornelius, Macke, Jakob H.
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Research on Modelling and Parameter Identification Method of Photovoltaic Arrays Based on the Implicit Double Diode Model and Reverse Bias Model

IET Renewable Power Generation
The establishment of an accurate photovoltaic (PV) arrays model is instrumental in enhancing the precision of PV performance evaluation and fault diagnosis, which holds significant importance for elevating the level of intelligent operation and ...
Zou Zubing, Bi Tianshu, Su Ying
doaj   +1 more source

Software complex for simulation modelling of single nucleotide genetic polymorphism sites

Informatika
Objectives. High-throughput sequencing methods have recently become widely used in the fundamental and applied research of various human diseases. Sequencing of functionally significant regions of the human genome enables the simultaneous identification ...
M. M. Yatskou, D. D. Sarnatski, V. V. Skakun, V. V. Grinev   +3 more
doaj   +1 more source

Experimental Methods of Validation for Numerical Simulation Results on Steel Flow through Tundish

Archives of Metallurgy and Materials, 2016
The article presents experimental results on the impact of tundish flow regulator influencing the liquid steel flow course. The research was conducted based on the hybrid modelling methods understood as a complementary use of Computational Fluid Dynamics
Pieprzyca J., Warzecha P., Merder T., Warzecha M.   +3 more
doaj   +1 more source