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A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

open access: yesAdvanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal   +21 more
wiley   +1 more source
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Simulation optimization

Proceedings of the 29th conference on Winter simulation - WSC '97, 1997
Simulation optimization can be defined as the process of finding the best input variable values from among all possibilities without explicitly evaluating each possibility. The objective of simulation optimization is to minimize the resources spent while maximizing the information obtained in a simulation experiment.
Yolanda Carson, Anu Maria
openaire   +2 more sources

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