Results 1 to 10 of about 7,798,024 (252)

Extended Simulation Function via Rational Expressions

open access: yesMathematics, 2020
In this paper, we introduce some common fixed point theorems for two distinct self-mappings in the setting of metric spaces by using the notion of a simulation function introduced in 2015.
Rawan Alsubaie   +3 more
doaj   +3 more sources

Modified Protein-Water Interactions in CHARMM36m for Thermodynamics and Kinetics of Proteins in Dilute and Crowded Solutions

open access: yesMolecules, 2022
Proper balance between protein-protein and protein-water interactions is vital for atomistic molecular dynamics (MD) simulations of globular proteins as well as intrinsically disordered proteins (IDPs).
Daiki Matsubara   +4 more
doaj   +1 more source

Global organization of neuronal activity only requires unstructured local connectivity

open access: yeseLife, 2022
Modern electrophysiological recordings simultaneously capture single-unit spiking activities of hundreds of neurons spread across large cortical distances. Yet, this parallel activity is often confined to relatively low-dimensional manifolds.
David Dahmen   +10 more
doaj   +1 more source

NNMT: Mean-Field Based Analysis Tools for Neuronal Network Models

open access: yesFrontiers in Neuroinformatics, 2022
Mean-field theory of neuronal networks has led to numerous advances in our analytical and intuitive understanding of their dynamics during the past decades.
Moritz Layer   +9 more
doaj   +1 more source

1024-channel electrophysiological recordings in macaque V1 and V4 during resting state

open access: yesScientific Data, 2022
Measurement(s) brain activity measurement • eye movement Technology Type(s) extracellular electrophysiology recording • multi-electrode array system • infrared camera Factor Type(s) visual stimulation Sample Characteristic - Organism Macaca ...
Xing Chen   +7 more
doaj   +1 more source

Dynamical Characteristics of Recurrent Neuronal Networks Are Robust Against Low Synaptic Weight Resolution

open access: yesFrontiers in Neuroscience, 2021
The representation of the natural-density, heterogeneous connectivity of neuronal network models at relevant spatial scales remains a challenge for Computational Neuroscience and Neuromorphic Computing.
Stefan Dasbach   +5 more
doaj   +1 more source

Reduced efficacy of a Src kinase inhibitor in crowded protein solution

open access: yesNature Communications, 2021
The intracellular compartment is a crowded environment. Here, the authors use molecular dynamics (MD) simulations to assess inhibitor binding to c-Src kinase and show how ligand binding pathways differ in crowded and dilute protein solutions ...
Kento Kasahara   +10 more
doaj   +1 more source

Common fixed point results via simulation type functions in non-Archimedean modular metric spaces and applications

open access: yesTopological Algebra and its Applications, 2022
In this study, we demonstrate the existence and uniqueness of common fixed points of a generalized (α,β)− simulation contraction on a non-Archimedean modular metric space.
Öztürk Mahpeyker, Girgin Ekber
doaj   +1 more source

Runtime Construction of Large-Scale Spiking Neuronal Network Models on GPU Devices

open access: yesApplied Sciences, 2023
Simulation speed matters for neuroscientific research: this includes not only how quickly the simulated model time of a large-scale spiking neuronal network progresses but also how long it takes to instantiate the network model in computer memory. On the
Bruno Golosio   +8 more
doaj   +1 more source

A Modular Workflow for Performance Benchmarking of Neuronal Network Simulations

open access: yesFrontiers in Neuroinformatics, 2022
Modern computational neuroscience strives to develop complex network models to explain dynamics and function of brains in health and disease. This process goes hand in hand with advancements in the theory of neuronal networks and increasing availability ...
Jasper Albers   +16 more
doaj   +1 more source

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