Results 31 to 40 of about 838,874 (266)
Energies, 2023 China is endowed with a large quantity of residual coal resources that require upward mining. The stability of interburden strata structures and accurate determination are crucial for safe mining. Therefore, we established a mechanical model of disturbed
Yujiang Zhang +6 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Theoretical Analysis of the Motorcycle Front Brake Heating Process during High Initial Speed Emergency Braking [PDF]
Journal of Applied and Computational Mechanics, 2020 Motorcycles are a common mode of transport. They are used both for a conventional purpose - as a way to cover the distance from A to B, but more and more often they are a way of recreation.
Andrzej Borawski +6 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
SNP-based heritability estimation using a Bayesian approach
Animal, 2013 Heritability is a central element in quantitative genetics. New molecular markers to assess genetic variance and heritability are continually under development. The availability of molecular single nucleotide polymorphism (SNP) markers can be applied for
K. Krag +4 more
doaj +1 more source
Evacuation Problem in Mosque Buildings, The Case of Konya Hacıveyiszade Mosque
Journal of Architectural Sciences and Applications, 2022 Evacuation of assembly buildings in emergencies such as earthquake, fire and terror is very important to prevent major casualties. To evacuate the building smoothly, it’s necessary to realize the right architectural design.
Hatice Sena Azkur, Murat Oral
doaj +1 more source
Simulation Study of BPPV Fatigability
Frontiers in Neurology, 2022 To analyze the mechanism and clinical significance of Benign paroxysmal positional vertigo (BPPV) fatigability and discuss how to eliminate BPPV fatigability. A physical simulation model of BPPV was developed to observe the effect of the Dix-Hallpike test on otolith location and explore strategies to eliminate fatigability.
Xiaokai Yang, Lidan Gao
openaire +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source