Results 31 to 40 of about 119,339 (216)

Inpatient Exposure, Confidence, and Knowledge in Pediatric Hematology/Oncology: Evaluating General Pediatric Residents During 2025 ACGME Curriculum Change

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background General pediatricians often evaluate hematologic and oncologic presentations before subspecialty consultation, yet the 2025 Accreditation Council for Graduate Medical Education (ACGME) pediatric requirements reduce inpatient pediatric hematology/oncology (PHO) time, raising questions about resident readiness.
Colburn Yu, Rohini Jain
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Simulation Study of BPPV Fatigability

open access: yesFrontiers in Neurology, 2022
To analyze the mechanism and clinical significance of Benign paroxysmal positional vertigo (BPPV) fatigability and discuss how to eliminate BPPV fatigability. A physical simulation model of BPPV was developed to observe the effect of the Dix-Hallpike test on otolith location and explore strategies to eliminate fatigability.
Xiaokai Yang, Lidan Gao
openaire   +3 more sources

SNP-based heritability estimation using a Bayesian approach

open access: yesAnimal, 2013
Heritability is a central element in quantitative genetics. New molecular markers to assess genetic variance and heritability are continually under development. The availability of molecular single nucleotide polymorphism (SNP) markers can be applied for
K. Krag   +4 more
doaj   +1 more source

A Disturbed Voussoir Beam Structure Mechanical Model and Its Application in Feasibility Determination of Upward Mining

open access: yesEnergies, 2023
China is endowed with a large quantity of residual coal resources that require upward mining. The stability of interburden strata structures and accurate determination are crucial for safe mining. Therefore, we established a mechanical model of disturbed
Yujiang Zhang   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Theoretical Analysis of the Motorcycle Front Brake Heating ‎Process during High Initial Speed Emergency Braking [PDF]

open access: yesJournal of Applied and Computational Mechanics, 2020
Motorcycles are a common mode of transport. They are used both for a conventional purpose - as a way to cover the distance from A to B, but more and more often they are a way of recreation.
Andrzej Borawski   +6 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Evacuation Problem in Mosque Buildings, The Case of Konya Hacıveyiszade Mosque

open access: yesJournal of Architectural Sciences and Applications, 2022
Evacuation of assembly buildings in emergencies such as earthquake, fire and terror is very important to prevent major casualties. To evacuate the building smoothly, it’s necessary to realize the right architectural design.
Hatice Sena Azkur, Murat Oral
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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