Results 61 to 70 of about 838,874 (266)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

The stability of IRT parameters under several test equating conditions

Frontiers in Psychology
IntroductionIt is crucial for researchers and test developers to compare results from different test sets (e. g., re-testing, parallel test forms). To ensure comparability, test sets are often linked using anchor items as a common denominator alongside ...
Dominik Weber, Nicolas Becker, Frank M. Spinath, Marco Koch   +3 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

A Single-Indicator Factor Approach for Correcting Measurement Error in Time-Varying Predictors in Developmental Research

Behavioral Sciences
Composite scores (e.g., mean or sum of survey items) are widely used as outcomes or predictors in psychological and social science research despite methodological concerns regarding measurement error.
Kejin Lee
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Population Median Estimation Using Auxiliary Variables: A Simulation Study with Real Data Across Sample Sizes and Parameters

Mathematics
This paper introduces an enhanced class of ratio estimators, which employ the transformation technique on an auxiliary variable under simple random sampling to estimate the population median.
Umer Daraz, Fatimah A. Almulhim, Mohammed Ahmed Alomair, Abdullah Mohammed Alomair   +3 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

A Study of Two Parameter Based an Exponential Probability Distribution: Properties and Applications

Engineering Reports
Defined on negative as well as positive domain, we introduce a novel two‐parameter survival distribution to offer enhanced flexibility and applicability in statistical modeling in the article understudy.
Sadaf Khan, Mohamed A. F. Elbarkawy, Abdus Saboor, Farrukh Jamal, Ehab M. Almetwally, Tehmina Naz, John T. Mendy, Mohammed Elgarhy   +7 more
doaj   +1 more source

Impacts of Design Parameters on the Thermal Performance of a Macro-Encapsulated Phase-Change-Material Blind Integrated in a Double-Skin Façade System

Energies
Double-skin façades (DSFs) are promising sustainable design elements of buildings. However, they are prone to overheating problems in warm seasons due to high outdoor temperatures and intense solar radiation.
Yilin Li, Wenshan He, Wanting Tao, Caiyi Yang, Yidong Li, Jo Darkwa   +5 more
doaj   +1 more source