Simultaneously quantifying<i>K</i><sub>1</sub>,<i>k</i><sub>2</sub>, and blood volume in myocardial imaging with overlapping volumes of interest: practical identifiability. [PDF]
Stentz DJ, Guerraty MA, Metzler SD.
europepmc +1 more source
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian +6 more
wiley +1 more source
Event-Triggered Adaptive Consensus Control for Nonlinear Multi-Agent Systems with Prescribed Performance and Full-State Constraints. [PDF]
Wang W +6 more
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Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali +4 more
wiley +1 more source
Synergic Improvement of Elastocaloric Effect in Polycrystalline NiMnGaCo by Magneto-Mechanical Coupling. [PDF]
Villa F +6 more
europepmc +1 more source
Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay +15 more
wiley +1 more source
The evolution of nonlinear mixed effects modeling in pharmacometrics: toward AI-based variational autoencoders. [PDF]
Rohleff J, Koch G, Schropp J.
europepmc +1 more source
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin +8 more
wiley +1 more source
Structural Entanglement from Interaction-Induced Fixed Points. [PDF]
Gunji YP, Khrennikov A.
europepmc +1 more source
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno +19 more
wiley +1 more source

