Results 61 to 70 of about 61,480 (263)

Dynamic loads and interference between meshing pairs in multi-stage geared system

Nihon Kikai Gakkai ronbunshu
Inside realistic multi-stage geared system the dynamic meshing tooth loads are in interference mutually between meshing pairs. This report deals with this multi-stage crosstalk theoretically by Receptance Operator Procedure (ROP) that has been developed ...
Masakazu KOJIMA
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Modelling and Simulation of Ternary Liquid-Phase Adsorption onto Activated Carbon

Adsorption Science & Technology, 2004
A computational procedure is presented for solving the set of rigid hyperbolic and parabolic partial differential equations describing the simultaneous adsorption of a ternary system in a column packed with adsorbent particles using the non-linear ...
Olaosebikan A. Olafadehan, Alfred A. Susu   +1 more
doaj   +1 more source

Beveridge Curve Shifts – Europe 2020 Perspectives

Scientific Annals of Economics and Business, 2016
The present paper aligns to the economic policy body of research granting intensive efforts to the sphere of analysing the unemployment rate’s evolution as well as its primary drivers and effects in the context of the Europe 2020 strategy.
Ferent-Pipas Marina
doaj   +1 more source

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

The Role of Financial Development Factors on How to Affect Oil Price on Oil and Gas Rents in Iran [PDF]

پژوهشهای اقتصادی, 2020
This paper investigates the role of financial development factors on how to affect oil price on oil and gas rents in Iran. In order to construct a multidimensional financial development index, the principal component analysis and weighted average of nine
fateme shamsolahrar fard, Majid Ahmadian, Nafiseh Behradmehr, Mohsen Mehrara, Ghahraman Abdoli   +4 more
doaj  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

FAKTOR-FAKTOR YANG MEMENGARUHI PDB INDONESIA DENGAN PERSAMAAN SIMULTAN 2SLS

E-Jurnal Matematika, 2012
Economic growth is indicated by an increase in the value of Gross Domestic Product (GDP). The size of GDP is influenced by various factors, including the Household Consumption, Investment, Government Spending, and Net Exports.
NI MADE SRI KUSUMAWARDHANI, I GUSTI AYU MADE SRINADI, MADE SUSILAWATI   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source