Massive Parallelization of Multibody System Simulation
This paper deals with the decrease in CPU time necessary for simulating multibody systems by massive parallelization. The direct dynamics of multibody systems has to be solved by a system of linear algebraic equations.
Michael Valášek, Ladislav Mráz
doaj
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
SEMIPARAMETRIC BAYESIAN ANALYSIS OF SIMULTANEOUS SYSTEMS WITH AN APPLICATION TO JAPANESE MEAT DEMAND [PDF]
This paper motivates and applies a variant of the Bayesian Bootstrap Multivariate Regression by Heckelei and Mittelhammer (2003) to a Japanese meat demand specification with endogenous regressors.
Heckelei, Thomas +2 more
core
SPECIES-SPECIFIC BIOMASS EQUATIONS FOR SMALL-SIZE TREE SPECIES IN SECONDARY TROPICAL FORESTS
Secondary tropical forests are largely dominated by small-diameter trees. Their contribution to the total stand productivity may be determinant for ecosystem functioning.
Ramiro Puc-Kauil +7 more
doaj
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Simulated Maximum Likelihood Estimation of the Linear Expenditure System with Binding Non-Negativity Constraints [PDF]
This paper discusses issues on the estimation of consumer demand equations subject to binding non-negative constraints. We propose computationally feasible specifications and a simulated maximum likelihood (SML) method for demand systems. Our study shows
Lung-fei Lee, Chihwa Kao, Mark M. Pitt
core
Topographic free surfaces and seismic anisotropy significantly modify seismic wave propagation. With increasing demands for high-precision subsurface imaging, advanced seismic prospecting and seismological imaging methods require simultaneous ...
Yu-Xuan Li +5 more
doaj +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Rotation Curves of Galaxies: A New Theoretical Approach and Comparison With Observations
Observational results on the rotation curve of a rotating galaxy are used in thought experiments. A binary system is inserted in the galaxy, and equations for radial accelerations of the two bodies are found.
J. Klačka
doaj +1 more source

