Results 71 to 80 of about 61,494 (263)

FAKTOR-FAKTOR YANG MEMENGARUHI PDB INDONESIA DENGAN PERSAMAAN SIMULTAN 2SLS

E-Jurnal Matematika, 2012
Economic growth is indicated by an increase in the value of Gross Domestic Product (GDP). The size of GDP is influenced by various factors, including the Household Consumption, Investment, Government Spending, and Net Exports.
NI MADE SRI KUSUMAWARDHANI, I GUSTI AYU MADE SRINADI, MADE SUSILAWATI   +2 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Dissolution dynamic nuclear polarization NMR studies of enzyme kinetics: Setting up differential equations for fitting to spectral time courses

Journal of Magnetic Resonance Open, 2019
: Dissolution dynamic nuclear polarization (dDNP) provides strikingly increased sensitivity for detecting NMR-receptive nuclei in molecules that are substrates of enzymes and membrane transport proteins.
Philip W. Kuchel, Dmitry Shishmarev
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Derivation and Application of a New Transmission Loss Formula for Power System Economic Dispatch

Energies, 2018
The expression and calculation of transmission loss (TL) play key roles for solving the power system economic dispatch (ED) problem. ED including TL must compute the total TL and incremental transmission loss (ITL) by executing power flow equations ...
Wei-Tzer Huang, Kai-Chao Yao, Ming-Ku Chen, Feng-Ying Wang, Cang-Hui Zhu, Yung-Ruei Chang, Yih-Der Lee, Yuan-Hsiang Ho   +7 more
doaj   +1 more source

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source

Bifurcation of Periodic Solutions of the Mackey– Glass Equation

Моделирование и анализ информационных систем, 2016
We study the bifurcation of the equilibrium states of periodic solutions for the Mackey– Glass equation. This equation is considered as a mathematical model of changes in the density of white blood cells.
E. P. Kubyshkin, A. R. Moryakova
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source