Results 31 to 40 of about 32,140 (247)

MAC Centered Cooperation - Synergistic Design of Network Coding, Multi-Packet Reception, and Improved Fairness to Increase Network Throughput [PDF]

, 2011
We design a cross-layer approach to aid in develop- ing a cooperative solution using multi-packet reception (MPR), network coding (NC), and medium access (MAC).
Cloud, Jason, Médard, Muriel, Zeger, Linda   +2 more
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Simultaneous acquisition of tracking data from two stations [PDF]

, 1975
A method and apparatus is described for obtaining simultaneous tracking data from two ground stations relative to a spacecraft, and in particular for obtaining two-way range and Doppler measurements with respect to the spacecraft using only one ...
Wood, G. E.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Research on Aperture‐Level Simultaneous Transceiver Technology Utilising an Improved Quantum Genetic Algorithm

IET Microwaves, Antennas & Propagation
Self‐interference (SI) suppression has always been critical for simultaneous transmit and receive (STAR) systems. To address the strong coupling between nearby transmit and receive antennas, this study employs an improved quantum genetic algorithm (IQGA)
Yong Bo, Hong Cao, Mouping Jin, Quan Wang, Wei Chen, Yong Ye, Lixia Yang   +6 more
doaj   +1 more source

Low-Cost Broadband RF Front-End Design for Enhanced Isolation in In-Band Full Duplex Radio

IEEE Journal of Microwaves
Future radios face the challenge of delivering faster data rates while efficiently utilizing the limited and regulated electromagnetic spectrum. In this context, broadband spectrum access in-band full-duplex (IBFD) operation using a simultaneous transmit
MD Rakibur Rahman, Satheesh Bojja Venkatakrishnan, John L. Volakis   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

A Protocol for Messaging to Extraterrestrial Intelligence

, 2011
Messaging to extraterrestrial intelligence (METI) is a branch of study concerned with constructing and broadcasting a message toward habitable planets.
Ball, Baum, Baum, Baxter, Benford, Bostrom, Cocconi, Denning, Des Marais, Devito, Dimitra Atri, Drake, Drake, Goldsmith, Grinspoon, Haqq-Misra, Hart, Jacob Haqq-Misra, Julia DeMarines, Kaplan, Lemarchand, Lomberg, Michaud, Sagan, Scheffer, Shuch, Sless, Tarter, Vakoch, Vakoch, Vakoch, von Hoerner, Ward, Webb, Zaitsev   +34 more
core   +1 more source