Results 121 to 130 of about 12,382 (265)

Small Airways Dysfunction and Remission in Adults With Asthma: A Longitudinal Exploratory Analysis of the AssessmenT of smalL Airways involvemeNT In aSthma (ATLANTIS) Study

open access: yesAllergy, EarlyView.
We conducted a post hoc analysis of ATLANTIS, a multinational prospective study including 684 adults with asthma. Fewer small airway symptoms and lower disease activity are independently associated with asthma remission. Replicated airway transcriptomic signatures show increased IL‐4/13 signalling and reduced coagulation pathways across the ATLANTIS ...
Akshi Kumar   +14 more
wiley   +1 more source

Educational technologies on signs of gestational risk and/or labor for pregnant women: a scoping review. [PDF]

open access: yesRev Esc Enferm USP
Silva TJP   +6 more
europepmc   +1 more source

Nasal Airway Transcriptome Reflects Selected Asthma‐Associated Gene Signatures in the Lower Airways

open access: yesAllergy, EarlyView.
Seven genes and two gene modules were consistently associated with asthma in both airway compartments in ARMS and were validated in ATLANTIS. The two modules reflected IL‐13 related inflammation and mast cell activity, respectively. Nasal gene signatures provide a non‐invasive proxy for selected bronchial asthma‐associated gene signatures. ARMS, Asthma
Hui Wen   +22 more
wiley   +1 more source

Non‐Invasive Scalp Tape‐Strip RNA Sequencing Captures Disease Activity and Treatment‐Response Signatures in Alopecia Areata

open access: yesAllergy, EarlyView.
Non‐invasive scalp tape‐strip RNA sequencing captures core immune and follicular molecular signatures in alopecia areata. Tape‐strip transcriptomic profiles reflect disease severity and treatment response to baricitinib, with concordance to scalp biopsy‐derived signatures.
Carmen Mochón‐Jiménez   +10 more
wiley   +1 more source

Anxiety and vital signs in cancer patients and music students before and after a music intervention: a quasi-experimental pilot study. [PDF]

open access: yesRev Lat Am Enfermagem
Caballero-de-la-Calle R   +5 more
europepmc   +1 more source

Navigating Oral Food Challenges in Clinical Trials to Keep the Science Moving Forward

open access: yesAllergy, EarlyView.
ABSTRACT The oral food challenge (OFC) has long been the reference standard for food allergy diagnosis, as well as to confirm natural development of oral tolerance. The utilization of OFCs has significantly broadened from its role in defining disease to defining participant eligibility, individual allergen reactivity thresholds and treatment outcomes ...
Edwin H. Kim   +10 more
wiley   +1 more source

Molecular Characterization of Non‐Specific Esophagitis Reveals a Distinct Non‐Eosinophilic Phenotype With Fibrotic Traits

open access: yesAllergy, EarlyView.
This study comprehensively characterizes non‐specific esophagitis and elucidates eosinophil‐independent fibrosis mechanisms. NSE appears to be a distinct fibrotic phenotype of the esophagus, without any considerable overlap with GERD and other chronic inflammatory disorders such as EoE or lymphocytic esophagitis.
Marc Pfefferle   +16 more
wiley   +1 more source

Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy

open access: yesAllergy, EarlyView.
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan   +16 more
wiley   +1 more source

Global Variation in Timing of Allergenic Food Introduction for Food Allergy Prevention: An International Survey of Healthcare Professionals

open access: yesAllergy, EarlyView.
This study examines the current state of food allergy prevention guideline implementation worldwide, identifying key variables that may explain the observed global variation. Among 731 healthcare professionals across 80 countries, geography and clinical specialty independently drove allergenic food introduction practices, creating an 8.5‐month practice
Agnes Sze‐yin Leung   +20 more
wiley   +1 more source

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