Results 61 to 70 of about 12,382 (265)

Glycopolymeric nanoparticles transported by activated platelets protect ischemic myocardium by alleviating PANoptosis through targeting macrophage Dectin‐1

BMEMat, EarlyView.
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu, Na Yang, Yan Zhang, Lingxin Peng, Yi Li, Yue Chao, Qinfang Miao, Haikun Qi, Jianhui Zhuang, Weixia Jian, Bingyu Li, Wenhui Peng, Jinghua Chen, Shiyu Gong   +13 more
wiley   +1 more source

Platelet FcɣRIIa Expression Refines Clinical Risk Assessment After Myocardial Infarction

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background In patients with myocardial infarction (MI), quantifying expression of platelet FcɣRIIa (pFCG) stratifies risk of subsequent MI, stroke, and death. Aims Assess the prognostic implications of clinical risk alone and in combination with the pFCG test.
David J. Schneider, Sean R. McMahon, Dominick J. Angiolillo, Alexander C. Fanaroff, Homam Ibrahim, Patrick K. Hohl, Brett L. Wanamaker, Mark B. Effron, Peter M. DiBattiste, behalf of the investigators   +9 more
wiley   +1 more source

AVALIAÇÃO DA LÍNGUA DE SINAIS, AQUISIÇÃO DE LÍNGUA DE SINAIS E ALFABETIZAÇÃO NA LÍNGUA DE SINAIS

Revista Brasileira de Alfabetização
As interfaces entre áreas da Educação e da Saúde beneficiam os Estudos Surdos e a comunidade surda. Uma das contribuições dessas áreas são os instrumentos de avaliação da língua de sinais e as possibilidades de uso desses instrumentos para o delineamento
Felipe Venâncio Barbosa, Sylvia Lia Grespan Neves   +1 more
doaj   +1 more source

Discharge Remote Monitoring Systems for Glycemic Management After Hospital Discharge

Chronic Diseases and Translational Medicine, EarlyView.
Heat map of median number of telehealth interactions by subgroup and theme. Major themes identified included intervention after remote monitoring alerts (e.g., “Team reached out to participant and instructed participant to treat hypo.”), insulin dose adjustments (e.g., “Participant reported that prednisone dose is increasing … Called to discuss insulin
Nirali Shah, Camilla Levister, Riana Jumamil, Carol Levy, Margaret Crawford, Christian Hicks, Selassie Ogyaadu, Aslihan Ipek, Abigail Tamru, Madeleine Rouviere, Leah Kaplan, Ying Xu, Harsimran Singh, Daniel Cherñavvsky, Grenye O'Malley   +14 more
wiley   +1 more source

Pediatric Developmental Safety Assessment: Are We Ready for the Next Thalidomide?

Clinical Pharmacology &Therapeutics, EarlyView.
Pediatric drug development has achieved remarkable success in the last 20 years with over 1,000 products studied in pediatric patients. This success has been driven in part by an increased understanding of pediatric disease processes. The aspect that has been largely overlooked is the potential adverse effect of new drugs on pediatric developmental ...
Gilbert J. Burckart, Susan M. Abdel‐Rahman, Gelareh Abulwerdi, Sherbet Samuels, Rebecca Racz, Mohamed A. Mohamoud, Nicholas P. Tatonetti   +6 more
wiley   +1 more source

Explorando a transformada wavelet contínua

Revista Brasileira de Ensino de Física
A transformada wavelet contínua constitui poderosa ferramenta para análise multiescala de dados. Ela tem amplas aplicações na Física, na Matemática, nas Ciências Naturais e, inclusive, grande apelo nas engenharias, computação e áreas de tecnologia e ...
M.O. Domingues, O. Mendes, M.K. Kaibara, V.E. Menconi, E. Bernardes   +4 more
doaj   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Responsive stimulation of the thalamus for idiopathic generalized epilepsy: Results of the randomized controlled NAUTILUS trial through 18 months

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the safety and effectiveness of responsive thalamic stimulation as adjunctive therapy for drug‐resistant idiopathic generalized epilepsy (IGE) with generalized tonic–clonic seizures (GTCSs). Methods NAUTILUS is a prospective, multicenter, single‐blind, randomized sham‐controlled pivotal trial ...
Utku Uysal, Patrick Landazuri, David E. Burdette, Sanjay Patra, Angela N. Crudele, Dario J Englot, Jay R. Gavvala, Sandipan Pati, Lesley C. Kaye, Steven Ojemann, Daniel Barnett, Joseph Neimat, Adriana E. Palade, Shervin Rahimpour, Amir A. Arain, Robert Mark Richardson, Sydney S. Cash, Vicenta Salanova, Alexandra Urban, William P. Welch, Jamie Joseph Van Gompel, Keith Starnes, David Spencer, Lia D. Ernst, Ushtar Amin, Angelica Rivera‐Cruz, Patricia Dugan, Marytery Fajardo, Matt Lallas, Barbara C. Jobst, Nicole Odom, Jarod L. Roland, Jon T. Willie, Sameer A. Sheth, Alica M. Goldman, Christopher T. Skidmore, Chengyuan Wu, Cornelia Drees, Jonathon Parker, Taneeta Mindy Ganguly, Jerzy Szaflarski, Saadi Ghatan, Lise Johnson, Jacob Norman, Brett Wingeier, Cairn G. Seale, Martha J. Morrell, Nautilus Study Group   +47 more
wiley   +1 more source

Accuracy of the rapid‐response electroencephalography's Automated Seizure Burden Estimator: A follow‐up validation study of version 8 (AccuRASE II)

Epilepsia, EarlyView.
Abstract Objective Ceribell Inc.'s point‐of‐care electroencephalographic (EEG) system and artificial intelligence‐based Automated Seizure Burden Estimator (ASBE; ClarityPro) have US Food and Drug Administration clearance for diagnosing electrographic status epilepticus (ESE).
Zubeda B. Sheikh, Michael W. K. Fong, Monica B. Dhakar, Wei Fang, Neishay Ayub, Janine Molino, Hiba A. Haider, Brandon Foreman, Emily J. Gilmore, Moshe Mizrahi, Ioannis Karakis, Sarah Schmitt, Gamaleldin Osman, Ji Yeoun Yoo, Lawrence J. Hirsch   +14 more
wiley   +1 more source

O parâmetro locação na Língua Brasileira de Sinais

Working Papers em Linguística
Este artigo apresenta um recorte de uma pesquisa mais ampla que investigou o parâmetro locação na Língua Brasileira de Sinais (Libras). Inicialmente introduzido nas pesquisas sobre a Língua Americana de Sinais (ASL) na década de 60 por Stokoe, o ...
Bruna Estefani Libano Alves, Aline Lemos Pizzio   +1 more
doaj   +1 more source