Results 111 to 120 of about 600 (148)
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39. Sincalide - the continuing saga
Nuclear Medicine Communications, 2001E A Clarke, A Notghi, S R Hesslewood
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Treatment of vincristine-induced ileus with sincalide, a cholecystokinin analog
Cancer Chemotherapy and Pharmacology, 1982Sincalide, a synthetic analog of cholecystokinin capable of stimulating bowel motility, has been administered to 12 patients with symptoms and signs of vincristine-induced ileus. Patients were given intravenous infusions of sincalide 0.01 microgram/kg/h over 2-24 h (mean, 8 h) for 1-12 days (mean, 5 days), usually until all evidence of ileus had ...
Don V Jackson, Wallace C Wu, C L Spurr
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Lyophilization of Sincalide and Correlation of Headspace Relative Humidity with Product Stability
Journal of Pharmaceutical Sciences, 1978An optimum freeze-drying cycle was developed for use with industrial equipment in the processing in vials of a product degraded by traces of moisture. The relative humidity of the headspace gas of the vials, which contained only 5 microgram of active ingredient, was monitored by a GC method and was then correlated with product stability.
R C, Huber, A O, Niedermayer, A L, Weiss
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Archives of Surgery, 1985
Thirty-six patients with biliary colic and normal oral cholecystograms, upper gastrointestinal tract roentgenograms, and results of gallbladder ultrasonography underwent sincalide-stimulated biliary excretion scanning. Nineteen of these patients subsequently underwent cholecystectomies.
Jack Pickleman
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Thirty-six patients with biliary colic and normal oral cholecystograms, upper gastrointestinal tract roentgenograms, and results of gallbladder ultrasonography underwent sincalide-stimulated biliary excretion scanning. Nineteen of these patients subsequently underwent cholecystectomies.
Jack Pickleman
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Classification Schema of Symptomatic Enterogastric Reflux Utilizing Sincalide Augmentation on Hepatobiliary Scintigraphy [PDF]
Enterogastric reflux (EGR) is the reflux of duodenal contents into the stomach. Hepatobiliary scintigraphy provides physiologic assessment of the biliary system and was used to test the hypothesis that presence and timing of EGR may be associated with infusion of sincalide, a surrogate of endogenous cholecystokinin.One hundred fifty-seven hepatobiliary
Matthew F Covington +1 more
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Studies of gallbladder contraction using intramuscular sincalide.
Radiology, 1983Intramuscular sincalide (the carboxy terminal octapeptide of cholecystokinin) was evaluated as an agent for producing gallbladder contraction. Following oral cholecystography 35 patients received intramuscular sincalide in one of two dosages, 18 patients received intravenous sincalide, and six patients were given intramuscular placebo.
C J, Rosenquist, T C, Barcia
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Journal of Clinical Gastroenterology, 1997
Although several approaches to overcome difficult bile duct cannulation and gain free biliary access have been popularized, the use of gastrointestinal peptide hormonal agents such as sincalide, a cholecystokinin agonist, as an alternative method has not been evaluated.
Allan P Weston
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Although several approaches to overcome difficult bile duct cannulation and gain free biliary access have been popularized, the use of gastrointestinal peptide hormonal agents such as sincalide, a cholecystokinin agonist, as an alternative method has not been evaluated.
Allan P Weston
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Normal Values for Sincalide Cholescintigraphy: Comparison of Two Methods
Radiology, 2001To establish normal gallbladder ejection fraction (GBEF) values for two sincalide (cholecystokinin [CCK]) infusion dose rates, 0.01 microg per kilogram of body weight infused for 3 minutes and 0.01 microg/kg infused for 60 minutes.Twenty healthy subjects were examined.
H A, Ziessman +3 more
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Compounded Versus Proprietary Sincalide for Evaluation of Gallbladder Ejection Fraction
Annals of Pharmacotherapy, 2004OBJECTIVE To report a comparison of compounded and proprietary sincalide in the evaluation of gallbladder ejection fraction during hepatobiliary scintigraphy. CASE SUMMARIES Two patients were referred to nuclear medicine with symptoms consistent with hepatobiliary dysfunction.
Daniel T, Guarasci +3 more
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Effect of Atropine and Sincalide on the Intestinal Uptake of F-18 Fluorodeoxyglucose
Clinical Nuclear Medicine, 1999Variable diffuse intestinal uptake of F-18 fluorodeoxyglucose (FDG) is commonly seen in patients undergoing positron emission tomography (PET) imaging. Diffuse high uptake can obscure a lesion, whereas occasional high focal uptake can mimic a lesion. The cause of intestinal FDG uptake and the parameters that influence the level of uptake are unknown.We
Hossein Jadvar, G M Segall
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