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Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
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Assessing NaV1.7 during tonic firing in pig C-nociceptors. [PDF]
Soares S +4 more
europepmc +1 more source
2D-Cosine power sine coupled map with fractal-Fibonacci fusion for hyperchaotic image encryption. [PDF]
Kumar M, Ch D.
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Trigonometric function transformation and its application in software reliability modeling. [PDF]
Vy DN +4 more
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Revisiting the impulse response creates an improved PID autotuner. [PDF]
Keyser R +3 more
europepmc +1 more source
Top-Down Scoring of Spectral Fitness by Image Analysis for Protein Structure Validation. [PDF]
Harding BD +6 more
europepmc +1 more source
Single-Cell RNA-Seq Profiling of Transposable Element Expression in Human Peripheral Blood Cells During Viral Infections. [PDF]
Fateev OD +12 more
europepmc +1 more source
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Forum Mathematicum, 2003
This paper is an English version of a part of some lecture notes by N. Kurokawa from 1991, the notes having been taken by S. Koyama. In the paper, a theory of multiple sine functions is constructed which generalizes the usual sine function. The double sine function was introduced by Hölder in 1886, and the authors introduce the triple and higher sine ...
Kurokawa Nobushige, Koyama Shin-ya
openaire +1 more source
This paper is an English version of a part of some lecture notes by N. Kurokawa from 1991, the notes having been taken by S. Koyama. In the paper, a theory of multiple sine functions is constructed which generalizes the usual sine function. The double sine function was introduced by Hölder in 1886, and the authors introduce the triple and higher sine ...
Kurokawa Nobushige, Koyama Shin-ya
openaire +1 more source

