Results 231 to 240 of about 343,701 (293)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Repeat-element RNAs integrate a neuronal growth circuit.

Cell
Zahavi EE, Koppel I, Kawaguchi R, Oses-Prieto JA, Briner A, Monavarfeshani A, Dalla Costa I, van Niekerk E, Lee J, Matoo S, Hegarty S, Donahue RJ, Sahoo PK, Ben-Dor S, Feldmesser E, Ryvkin J, Leshkowitz D, Perry RB, Cheng Y, Farber E, Abraham O, Samra N, Okladnikov N, Alber S, Albus CA, Rishal I, Ulitsky I, Tuszynski MH, Twiss JL, He Z, Burlingame AL, Fainzilber M.   +31 more
europepmc   +1 more source

Excitation and polarization of isolated neurons by high-frequency sine waves for temporal interference stimulation. [PDF]

Cell Rep Phys Sci
Semenov I, Kim V, Silkuniene G, Pakhomov AG.   +3 more
europepmc   +1 more source

An integration of deep learning models for effective classification of human activity patterns in disabled people using gesture analysis. [PDF]

Sci Rep
Alkahtani HK, Al-Kahtani N, Mohammed GP, Marzouk R.   +3 more
europepmc   +1 more source

An acceleration-only modal circle-fitting method for in-situ fatigue damage detection. [PDF]

Sci Rep
Kang DS, Bae SH, Baek S.
europepmc   +1 more source

Endovascular repair of type B acute aortic syndromes involving the left subclavian artery: A retrospective single-centre study. [PDF]

PLoS One
Kang M, Zhao Y, Meng Y, Ma Q, Zhang J, Qin H, Tian H.   +6 more
europepmc   +1 more source

Identification of ADAR1i-124: The first effective A-to-I RNA editing inhibitor with promising cancer therapeutic potential. [PDF]

iScience
Minakuchi M, Zhang H, Cassel J, Shiromoto Y, Villanueva J, Skordalakes E, Salvino JM, Li Q, Nishikura K.   +8 more
europepmc   +1 more source

Comparative RNA-Seq Analysis of Colon Spheroids and Patient-derived Tissues Identifies Non-Canonical Transcript Isoforms of Protein-Coding Genes Implicated in Colon Carcinogenesis. [PDF]

Cancer Inform
Babic T, Banovic Djeri B, Pavlovic D, Dragicevic S, Despotovic J, Karanovic J, Nikolic A.   +6 more
europepmc   +1 more source

Remodeling Activity of ChAHP Restricts Transcription Factor Access to Chromatin

Ahel J, Mohn F, Schwaiger M, Kaaij L, Steiner J, Moreno EPF, Hess D, Bühler M.   +7 more
europepmc   +1 more source