Results 131 to 140 of about 1,324,526 (310)
Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion
Advanced Science, EarlyView.The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li +10 more
wiley +1 more source
Foreign Labor Trends: Singapore [PDF]
, 2003 Foreign Labor Trendssingapore_2003.pdf: 2178 downloads, before Oct.
U.S. Department of Labor
core +1 more source
Advanced Science, EarlyView.Confinement by nanoscale covalent organic frameworks reinforces hydrogels, imparting exceptional mechanical strength and ionic conductivity for high‐performance electrolyte applications. ABSTRACT Hydrogels are widely applied in various fields, including energy storage and flexible electronics. However, their mechanical properties often fail to meet the
Peiyao Yan +15 more
wiley +1 more source
Recent Methodological Opportunities in Online Hypermedia – a Case Study of Photojournalism in Singapore [PDF]
This methodological paper reviews the recent work done by photojournalists in Singapore who have leveraged on the use of multimedia to create meaning-rich narratives of the social situations they investigate.
Terence Heng
core
Advanced Science, EarlyView.A neutrophil‐membrane‐camouflaged nanoplatform (RC@NMVs) exploits tumor inflammation to target and accumulate in tumors. Intracellular Ca2+ overload is triggered via lysosomal CaP dissolution and Ru red‐mediated Ca2+ channel blockade, synergistically inducing gasdermin‐mediated pyroptosis.
Yingying Liu +8 more
wiley +1 more source
Doing Business in Singapore [PDF]
, 2005 [Exerpt] Singapore, a Republic with a multi-racial population of over 4 million, is an attractive place in which to do business. It has an enviable record of political stability and the government actively encourages investment by foreign business ...
Baker & McKenzie
core +1 more source
Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare
Advanced Science, EarlyView.Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu +10 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li +4 more
wiley +1 more source
Economic Fundamentals and Managed Floating Exchange Rate Regime in Singapore [PDF]
¡°Pegging the Singapore dollar to a basket of currencies instead of a fixed rate to the US dollar and having a transparent system were claimed by the government of Singapore to have enabled the country to weather the Asian financial crisis better.
Choo Lay Har, Reza Y. Siregar
core