Results 241 to 250 of about 1,324,526 (310)

A smoothing and bootstrap-based framework for early outbreak detection. [PDF]

PLoS One
Wang L, Xia Y, Goh EH, Chen M.
europepmc   +1 more source

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

British Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang, Jennifer A. Winton, Kyle T. Matschke, Alexandre Stouffs, Kimberly C. Lee, Yuanyuan Zhang, Wenlian Qiao, Weiwei Tan   +7 more
wiley   +1 more source

Author Correction: Enterovirus-A71 exploits peripherin and Rac1 to invade the central nervous system. [PDF]

EMBO Rep
Lim ZQ, Ng QY, Oo Y, Chu JJH, Ng SY, Sze SK, Alonso S.   +6 more
europepmc   +1 more source

Lifestyle factors and DNA methylation-based aging clocks: cross-sectional and longitudinal associations in the Singapore diet and healthy aging cohort. [PDF]

J Prev Alzheimers Dis
Shan J, Tay JH, Ye KX, Guo J, Cao L, Zeng Y, Lee TS, Heok KE, Kennedy BK, Maier AB, Feng L.   +10 more
europepmc   +1 more source

Epigenome-Wide Association Study in Asian Cohort Identifies Novel DNA Methylation Markers for Carotid Intima-Media Thickness

Tan K, Harris SE, Maddock J, Tay D, Jain PR, Science H, Mok SQ, Hebrard M, Schminke U, Xue CC, Goh LL, Mina TH, Teumer A, Lim WK, Leong KP, Yeo KK, Cheng C, Sim X, Lee ES, Wardlaw JM, Völzke H, Wong A, Cox SR, Dalan R, Dehghan A, Loh M.   +25 more
europepmc   +1 more source

Regulation of clinical Artificial Intelligence (AI) in the Age of Agents: Unconfined Non-Deterministic Clinical Software (UNDCS) systems for healthcare. [PDF]

NPJ Digit Med
Tan C, Gunasekeran DV, Low CO, Sim GSY, Foo DY, Morris RJT, Wong TY.   +6 more
europepmc   +1 more source

Identification of immunogenic neoantigens from intron retention in colorectal cancer. [PDF]

Sci Rep
Manoharan T, Kee BBR, Cheng CZM, Choy MK, Siew BE, Cheong WK, Lee KY, Tan IJ, Lieske B, Yap CK, Tan IBH, Tan KK, Tan KT, Chia G.   +13 more
europepmc   +1 more source

Mapping educational scholarship in a mixed-financing health system: a scoping review of health professions education research in Singapore. [PDF]

BMC Med Educ
Yeo MM, Narayan A, Tan BCY, Ng MSL, Tan HK, Navedo DD.   +5 more
europepmc   +1 more source

Reply to determining MCID threshold for Knee Society Score to assess patient satisfaction in knee arthroplasty. [PDF]

NPJ Digit Med
Liu X, Liu Y, Lee ML, Hsu W, Liow MHL.
europepmc   +1 more source