Advanced Science, EarlyView.We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng +8 more
wiley +1 more source
ATDD: Multi-lingual dataset for auto-tune detection in music recordings. [PDF]
Data BriefGohari M +3 more
europepmc +1 more source
Highly Aligned Bacteria Cellulose Yarn Aggregation for Energy Generation and Strain Sensing
Advanced Science, EarlyView.Although high‐performance bacterial cellulose fibers have attracted significant interest for wearable electronics, a self‐powered and high‐mechanosensitive design is still scarce for achieving an intelligent integrated system. Here, we demonstrate an innovative bio‐fabrication strategy to develop a core‐sheath yarn that features the ordered network and
Chong Gao +9 more
wiley +1 more source
Advanced Science, EarlyView.Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia +4 more
wiley +1 more source
Depression, anxiety, and mental state in patients with early-stage dementia: comparison of reminiscence therapy and cognitive stimulation therapy. [PDF]
Dement NeuropsycholDemir ZG +3 more
europepmc +1 more source
Harnessing Phase Separation for the Development of High‐Performance Hydrogels
Advanced Science, EarlyView.ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao +3 more
wiley +1 more source
Multi‐Functional Adaptive Interfaces for Next‐Generation Wearable and Implantable Bioelectronics
Advanced Science, EarlyView.Adaptive Biointerfaces: A comprehensive overview of next‐generation bioelectronics is presented, highlighting mechano‐adaptive and biophysiologically adaptive interfaces that enable stable, long‐term integration with living tissues. As illustrated in the image, adaptive interface strategies, including mechano‐adaptivity (e.g., injectability, shape ...
Jinhong Park +7 more
wiley +1 more source
Cognitive enhancement through music therapy: meta-analytic evidence across clinical population. [PDF]
Front Public HealthMulia GJ +6 more
europepmc +1 more source
Distinct Biotypes of Visual Perception in Major Depressive Disorder
Advanced Science, EarlyView.In a discover dataset (272 acute MDD patients), this work identifies a novel depression biotype characterized by impaired visual motion perception, using machine learning clustering. An independent dataset confirms the robustness of this biotype through cross‐validation and demonstrates its generalizability.
Zhuoran Cai +13 more
wiley +1 more source
The effect of group singing interventions on health biomarkers in people with stigmatising conditions: a scoping review protocol. [PDF]
Syst RevBouguettaya A, Reeves K, Tat P, Tan JY.
europepmc +1 more source