Results 151 to 160 of about 651,227 (267)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Decoding the Therapeutic Effects of Acupuncture in Hemorrhagic Stroke Using Single-Cell RNA Sequencing. [PDF]

CNS Neurosci Ther
Ruan C, Du J, Zhang W, Song J, Feng P, Shi J, Lou K, Lu Y, Li X, Guo Z, Liu H.   +10 more
europepmc   +1 more source

Temporally integrated single cell RNA sequencing analysis of PBMC from experimental and natural primary human DENV-1 infections

, 2021
Adam T. Waickman, Heather Friberg, Gregory D. Gromowski, Wiriya Rutvisuttinunt, Tao Li, Hayden Siegfried, Kaitlin Victor, Michael K. McCracken, Stefan Fernandez, Anon Srikiatkhachorn, Damon W. Ellison, Richard G. Jarman, Stephen J. Thomas, Alan L. Rothman, Timothy P. Endy, Jeffrey R. Currier   +15 more
openalex   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Deciphering B Cell Heterogeneity and Pathogenic Mechanisms in Osteoporosis Through Single-Cell RNA Sequencing. [PDF]

Biomed Res Int
Zhou T, Zheng J, Sun Y, Wu J, Liu W, Zheng Z, Li J, Fu G, Zhang F, Chen Y, Zeng G, Song W.   +11 more
europepmc   +1 more source

Insights into the Biology of Hearing and Deafness Revealed by Single-Cell RNA Sequencing. Ranum et al.

, 2019
Richard J. Smith
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Single-cell RNA sequencing identifies ZBP1-dependent mechanisms in OSCC progression. [PDF]

Cell Death Dis
Lin X, Wang C, Li C, Wu J, Zhang P, Zhang C, Chen H, Xu F, Zhang S, Luo C, Tang C.   +10 more
europepmc   +1 more source

The Risk Genes S1PR5, CMC1, and ASAH1 as Potential Targets for the Diagnosis, Immunotherapy, and Treatment of Colon Adenocarcinoma by Single-Cell and Bulk RNA Sequencing Analysis

Zipeng Xu, Jun Gong, Weidong Hu, Ge Chen, G TONG, Feng Cai, Zhenghai Zhu, Yihang Yuan, Chaobo Chen   +8 more
openalex   +1 more source