Results 201 to 210 of about 651,227 (267)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Identifying potential therapeutic targets in lung adenocarcinoma: a multi-omics approach integrating bulk and single-cell RNA sequencing with Mendelian randomization [PDF]

Youpeng Chen, Enzhong Li, Zhenglin Chang, Tingting Zhang, Zhenfeng Song, Haojie Wu, Zhangkai J. Cheng, Baoqing Sun   +7 more
openalex   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Molecular characterization of directly reprogrammed neurons from human fibroblasts using single cell RNA sequencing. [PDF]

Sci Rep
Seo DJ, Kim JA, Lee JH, Hong YH.
europepmc   +1 more source

Additional file 1 of Single-cell RNA sequencing reveals disease associated changes in brain endothelial cells in the 5XFAD mouse

Rebecca Embalabala, Haley Masters, Elaina MaryElizabeth Ziehm, Jamie Pouncey, Hyosung Kim, Ethan S. Lippmann   +5 more
openalex   +1 more source

demuxSNP: supervised demultiplexing single-cell RNA sequencing using cell hashing and SNPs [PDF]

Michael P. Lynch, Yufei Wang, Shannan Ho Sui, Laurent Gatto, Aedín C. Culhane   +4 more
openalex   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

scExplorer: a comprehensive web server for single-cell RNA sequencing data analysis. [PDF]

Bioinform Adv
Hernández-Galaz S, Hernández-Olivera A, Villanelo F, Lladser A, Martin AJM.   +4 more
europepmc   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

A systematic evaluation of highly variable gene selection methods for single-cell RNA-sequencing. [PDF]

Genome Biol
Zhao R, Lu J, Li Y, Zhou W, Zhao N, Ji H.   +5 more
europepmc   +1 more source