Results 211 to 220 of about 651,227 (267)

Integrative analysis of single-cell RNA sequencing, bulk RNA sequencing, and proteomic data identified NOTCH3 as a hub gene contributing to human intervertebral disc fibrosis [PDF]

Qi Ding, Xi Chen, Quan Zheng, Qiangbing Dou, Chuanhong Zuo, Qiwei Wang, Cailiang Shen   +6 more
openalex   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Integrating single-cell RNA sequencing with spatial transcriptomics reveal the fibrosis-related genes in hepatocellular carcinoma. [PDF]

Front Immunol
Qiao W, Li L, Jin R, Hu C.
europepmc   +1 more source

Integrated single-cell and bulk RNA sequencing analysis establishes a cancer associated fibroblast-related signature for predicting prognosis and therapeutic responses in neuroblastoma [PDF]

Zheng Cao, Qi Wang, Yali Han, Jianwei Lin, Qi Wu, Chencheng Xu, Jingchun Lv, Lei Zhang, Hongxiang Gao, Dapeng Jiang   +9 more
openalex   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

CellMentor: cell-type aware dimensionality reduction for single-cell RNA-sequencing data. [PDF]

Nat Commun
Hevdeli O, Petrenko E, Aran D.
europepmc   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Phylogenetic tree inference from single-cell RNA sequencing data

Zimmermann N, Sun X, Hård J, Kuipers J, Beerenwinkel N.   +4 more
europepmc   +1 more source

Unveiling the dental cellular landscape: A comprehensive review of single-cell RNA sequencing in human dental tissues. [PDF]

Jpn Dent Sci Rev
Shah MS, Kondo T, Sundarabupathi M, Samaranayake LP, Jamal M, Egusa H.   +5 more
europepmc   +1 more source

Supplementary Table S4 from Single-Cell RNA Sequencing Unifies Developmental Programs of Esophageal and Gastric Intestinal Metaplasia

Karol Nowicki-Osuch, Lizhe Zhuang, Tik Shing Cheung, Emily L. Black, Neus Masqué‐Soler, Ginny Devonshire, Aisling M. Redmond, Adam Freeman, Massimiliano di Pietro, Nastazja Pilonis, Władysław Januszewicz, Maria O’Donovan, Simon Tavaré, Jacqueline D. Shields, Rebecca C. Fitzgerald   +14 more
openalex   +1 more source