Results 41 to 50 of about 31,349 (221)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Force between magnetic nanoplates with dipolar interactions

Nano Express, 2023
This study considers the dependence of the force caused by the dipolar interaction between small low-dimensional magnets such as single-molecule magnets and two-dimensional magnets on the distance between them within the framework of the dipolar Ising ...
Norio Inui
doaj   +1 more source

Polarized Neutron Diffraction: An Excellent Tool to Evidence the Magnetic Anisotropy—Structural Relationships in Molecules

Magnetochemistry, 2021
This publication reviews recent advances in polarized neutron diffraction (PND) studies of magnetic anisotropy in coordination compounds comprising d or f elements and having different nuclearities.
Dominique Luneau, Béatrice Gillon
doaj   +1 more source

Berry-phase blockade in single-molecule magnets

, 2006
We formulate the problem of electron transport through a single-molecule magnet (SMM) in the Coulomb blockade regime taking into account topological interference effects for the tunneling of the large spin of a SMM.
A. Garg, Gabriel González, K. Blum, L. Gunther, Michael N. Leuenberger   +4 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Series of Chloranilate-Bridged Dinuclear Lanthanide Complexes: Kramers Systems Showing Field-Induced Slow Magnetic Relaxation

Magnetochemistry, 2019
A series of chloralilate-bridged dinuclear lanthanide complexes of formula [{LnIII(Tp)2}2(μ-Cl2An)]·2CH2Cl2, where Cl2An2− and Tp− represent the chloranilate and hydrotris (pyrazolyl)borate ligands, respectively, and Ln = Gd (1), Tb
Ryuta Ishikawa, Shoichi Michiwaki, Takeshi Noda, Keiichi Katoh, Masahiro Yamashita, Satoshi Kawata   +5 more
doaj   +1 more source

Lanthanide-Based Single-Molecule Magnets Derived from Schiff Base Ligands of Salicylaldehyde Derivatives

Inorganics, 2020
The breakthrough in Ln(III)-based SMMs with Schiff base ligands have been occurred for the last decade on account of their magnetic behavior, anisotropy and relaxation pathways.
Mamo Gebrezgiabher, Yosef Bayeh, Tesfay Gebretsadik, Gebrehiwot Gebreslassie, Fikre Elemo, Madhu Thomas, Wolfgang Linert   +6 more
doaj   +1 more source

Time relaxation of interacting single--molecule magnets

, 2005
We study the relaxation of interacting single--molecule magnets (SMMs) in both spatially ordered and disordered systems. The tunneling window is assumed to be, as in Fe8, much narrower than the dipolar field spread.
A. Abragam, I. S. Gradshteyn, J. J. Alonso, Juan J. Alonso, Julio F. Fernández, M. Novak   +5 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source