Results 41 to 50 of about 38,930 (309)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A universal ligand mediated method for large scale synthesis of transition metal single atom catalysts

Nature Communications, 2019
Single-atom catalysts are a promising class of catalytic materials, but general synthetic methods are limited. Here, the authors develop a ligand-mediated strategy that allows the large-scale synthesis of diverse transition metal single atom catalysts ...
Hongzhou Yang, Lu Shang, Qinghua Zhang, Run Shi, Geoffrey I. N. Waterhouse, Lin Gu, Tierui Zhang   +6 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Ni Single Atom Catalysts for CO₂ Activation [PDF]

Journal of the American Chemical Society, 2019
We report on the activation of CO2 on Ni single-atom catalysts. These catalysts were synthesized using a solid solution approach by controlled substitution of 1-10 atom % of Mg2+ by Ni2+ inside the MgO structure. The Ni atoms are preferentially located on the surface of the MgO and, as predicted by hybrid-functional calculations, favor low-coordinated ...
Marie-Mathilde Millet, Gerardo Algara-Siller, Sabine Wrabetz, Aliaksei Mazheika, Frank Girgsdies, Detre Teschner, Friedrich Seitz, Andrey Tarasov, Sergey V. Levchenko, Robert Schlögl, Elias Frei   +10 more
openaire   +4 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Strain Engineering of Single‐Atom Catalysts for Electrochemical Conversion

ChemElectroChem
Strain engineering is an effective approach for modulating the activity of single‐atom catalysts, yet the underlying mechanisms are not fully understood.
Youxuan Ni, Yong Lu, Weiwei Xie, Jun Chen   +3 more
doaj   +1 more source

Regulating the electronic structure through charge redistribution in dense single-atom catalysts for enhanced alkene epoxidation

Nature Communications, 2023
Inter-site interaction in densely populated single-atom catalysts has been demonstrated to have a crucial role in regulating the electronic structure of metal atoms, and consequently their catalytic performances.
Hongqiang Jin, Kaixin Zhou, Ruoxi Zhang, Hongjie Cui, Yu Yu, Peixin Cui, Weiguo Song, Changyan Cao   +7 more
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Recent Advances in Multi-Atom Catalysts for Sustainable Energy Applications

Molecules
Single-atom catalysts characterized by their novel electronic configurations and exceptional atomic utilization efficiency have emerged as potential alternatives to costly noble metal catalysts, garnering extensive research attention in various ...
Qing Wang, Bo Cheng, Shichang Cai, Xiaoxiao Li, Di Lu, Naying Zhang, Chaoqun Chen, Hanlu Zhang, Yagang Feng, Lei Duan, Shaoyong Qin, Zihan Meng   +11 more
doaj   +1 more source

The simplest construction of single-site catalysts by the synergism of micropore trapping and nitrogen anchoring

Nature Communications, 2019
Single-atom catalysts maximize atom usage within supports, but preparations can be complex. Here, authors show a facile impregnation-adsorption method to attach single noble-metal atoms to N-doped porous carbon and demonstrate strong electrocatalytic ...
Zhiqi Zhang, Yugang Chen, Liqi Zhou, Chi Chen, Zhen Han, Bingsen Zhang, Qiang Wu, Lijun Yang, Lingyu Du, Yongfeng Bu, Peng Wang, Xizhang Wang, Hui Yang, Zheng Hu   +13 more
doaj   +1 more source