Results 241 to 250 of about 1,198,587 (324)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Decoding the Cellular Heterogeneity and Malignant Progression of Human Penile Squamous Cell Carcinoma by Single-Cell RNA Sequencing. [PDF]

Adv Sci (Weinh)
Hu X, Shi W, Dong L, Huang L, Zhang X, Feng Y, Sun J, Liu L, Liu T, Fu J, Zhong B, Leng Q, Wu X, Chen M, Li L, Li Y, Jin X, Wang L, Cao J, Li X, Yin M, Chen X.   +21 more
europepmc   +1 more source

Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing data reveals hidden subpopulations of cells

Nature Biotechnology, 2015
F. Buettner, K. Natarajan, F. P. Casale, V. Proserpio, A. Scialdone, Fabian J Theis, S. Teichmann, J. Marioni, O. Stegle   +8 more
semanticscholar   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Evaluating imputation methods for accurate estimation of cell population fractions in single-cell RNA sequencing. [PDF]

NAR Genom Bioinform
Valyaeva AA, Tochilkina MS, Sheval EV.
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Characterization of T cell markers in endometrial carcinoma through single-cell RNA sequencing. [PDF]

Discov Oncol
Zhao M, Zhou L.
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Correction to "A comparison of integration methods for single-cell RNA sequencing data and ATAC sequencing data". [PDF]

Quant Biol
Kan Y, Wang W, Qi Y, Zhang Z, Liang X, Jin S.   +5 more
europepmc   +1 more source

A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing [PDF]

, 2019
Chen, David Y., Church, Deanna M., Fiddes, Ian T., Fronick, Catrina C., Fulton, Robert S., Ley, Timothy J., Miller, Christopher A., Petti, Allegra A., Srivatsan, Sridhar N., Williams, Stephen R.   +9 more
core   +1 more source