Results 311 to 320 of about 1,198,587 (324)

Single-cell RNA-Sequencing in Neuroscience

Neuroforum, 2019
Summary Technical innovations in the last decade have allowed to sequence transcriptomes of single cells. Single-cell RNA-sequencing (scRNA-seq) has since then opened the window to a deeper understanding of cellular identity and is becoming a widely used method in molecular biology.
Simone Mayer, Shokoufeh Khakipoor, Maxim A. Drömer, Daniel A. Cozetto   +3 more
openaire   +1 more source

Single-Cell RNA Sequencing of Glioblastoma Cells

2018
Single-cell RNA sequencing (sc-RNASeq) is a recently developed technique used to evaluate the transcriptome of individual cells. As opposed to conventional RNASeq in which entire populations are sequenced in bulk, sc-RNASeq can be beneficial when trying to better understand gene expression patterns in markedly heterogeneous populations of cells or when
Rajeev, Sen, Igor, Dolgalev, N Sumru, Bayin, Adriana, Heguy, Aris, Tsirigos, Dimitris G, Placantonakis   +5 more
openaire   +2 more sources

Single Cell Micro RNA Sequencing Library Preparation

Micro RNAs represent important post-transcriptional regulators in health and are involved in the onset of many diseases. Therefore, the further characterization of physiological miRNA functions is an important basic research question, and miRNAs even have high potential as biomarkers both for prognosis and diagnosis. In order to exploit this potential,
Sarah M, Hücker, Stefan, Kirsch
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Stories in Single Cell RNA Sequencing

2022
This thesis describes the projects I have worked on since starting the Caltech bioengineering program in fall 2017. The general theme of my projects is that they are all about single cell RNA sequencing (scRNA-seq), spanning the experimental and computational realms.
openaire   +1 more source

Cancer cell states: Lessons from ten years of single-cell RNA-sequencing of human tumors.

Cancer Cell
Human tumors are intricate ecosystems composed of diverse genetic clones and malignant cell states that evolve in a complex tumor micro-environment. Single-cell RNA-sequencing (scRNA-seq) provides a compelling strategy to dissect this intricate biology ...
I. Tirosh, M. Suvà
semanticscholar   +1 more source

Single-Cell RNA Sequencing

2023
Robert Morris, Feng Cheng
openaire   +1 more source

Studying Cancer Heterogeneity by Single-Cell RNA Sequencing

2019
A major hurdle for the treatment of cancer is the incomplete understanding of its evolution through the course of its emergence, dispersal, and relapse. Genetic and epigenetic changes in combination with external cues and selective forces are the driving factors behind tumor heterogeneity.
Johannes W, Bagnoli, Lucas E, Wange, Aleksandar, Janjic, Wolfgang, Enard   +3 more
openaire   +2 more sources

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

Nature Neuroscience, 2014
D. Usoskin, Alessandro Furlan, S. Islam, Hind Abdo, P. Lönnerberg, Daohua Lou, J. Hjerling-Leffler, J. Haeggström, O. Kharchenko, P. Kharchenko, S. Linnarsson, P. Ernfors   +11 more
semanticscholar   +1 more source

Single-Cell RNA-Sequencing of RVFV Infection

On the RNA level, viral infections are characterized by perturbations in the host cell transcriptome as well as the development of viral genetic information. Investigating the abundance and dynamic of RNA molecules can provide ample information to understand many aspects of the infection, from viral replication to pathogenesis.
openaire   +2 more sources

Single-Cell RNA Sequencing Analysis: A Step-by-Step Overview.

Methods in molecular biology, 2021
Shaked Slovin, A. Carissimo, F. Panariello, Antonio Grimaldi, V. Bouché, G. Gambardella, D. Cacchiarelli   +6 more
semanticscholar   +1 more source