Results 171 to 180 of about 731,457 (305)

Single-Cell RNA Sequencing Reveals That C5AR1 in Follicle Monocyte Cells Could Predict the Development of POI

Ying Han, Junrong Diao, Xinyan Wang, Shuai Zhang, Lina Yuan, Yaqiong Ping, Yunshan Zhang, Haining Luo Tianjin Central Hospital of Obstetrics and Gynecology/Nankai University Affiliated Maternity Hospital, Tianjin Key Laboratory of Human Development and ...
Diao J, Ping Y, Zhang Y, Yuan L, Han Y, Wang X, Luo H, Zhang S   +7 more
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Empowering fungal infection research with single-cell RNA sequencing. [PDF]

Commun Biol
Toth R, Cabarrubias FR, Czimmerer Z, Vecsernyes-Nagy K, Gacser A.   +4 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Multisite Assessment of Methods for Cell Preservation Upstream of Single-Cell RNA Sequencing. [PDF]

J Biomol Tech
Kolling Iv FW, Podnar JW, Wilkins O, Fraser CJ, MacDonald ML, Polson SW, Hebert ZT, Chittur SV, Hayden A, Kuentzel M, Heinz M, Huerta GM, Stevenson HS, Karmakar A, Fronick C, Cook L, Vargas S, Xuei X, McGuire P, Zeller M, Zhang Y, Dai R, Wang X, Wai CM, Thimmapuram J, Arora D, Mesa T, Fan J, Alekseyev YO, Cervone F, Williams C, Gorham N, Lemenze A, Goodwin S, Preall J, Whittaker CA.   +35 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Bibliometric analysis of single-cell RNA sequencing in tumor microenvironment. [PDF]

Discov Oncol
Ma J, Chen T, Shen K, Fang M, Zhang Y, Yang L, Guo L.   +6 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

The recent advancements of single-cell RNA sequencing in pre-eclampsia. [PDF]

Front Med (Lausanne)
Tang S, Lin X.
europepmc   +1 more source