Results 211 to 220 of about 642,878 (258)

Modulation of Inflammatory and Oxidative Stress Pathways in COPD: Unraveling the Mechanisms of Fenugreek Through Network Pharmacology and Single-Cell RNA Sequencing. [PDF]

Int J Chron Obstruct Pulmon Dis
Aikeranmu B, Maimaitiyiming D, Aierken H.   +2 more
europepmc   +1 more source

Single-patient single-cell RNA sequencing reveals neuroendocrine predominance and immunosuppression in small-cell lung cancer. [PDF]

Transl Cancer Res
Wang Y, He S, Wang R, Huang W.
europepmc   +1 more source

Removal of unwanted variation in pseudobulk analysis of single-cell RNA sequencing data and the leveraging of pseudoreplicates. [PDF]

NAR Genom Bioinform
Prieto León S, De Troyer E, Geys H, Van den Berge K, Thas O.   +4 more
europepmc   +1 more source

Leveraging two novel droplet-based single-cell RNA Sequencing platforms: a comparative study with 10x genomics. [PDF]

BMC Genomics
Maluchenko AV, Avsievich ES, Zvorygina IS, Antysheva ZG, Maksimov DO, Boytsova MV, Tabakov DV, Bodunova NA, Glazova OV, Tychinin DI, Bolbat AV, Petriaikina ES, Svetlichnyy DV, Yudin SM, Keskinov AA, Yudin VS, Woroncow MV, Skvortsova VI, Krupinova JA, Volchkov PY.   +19 more
europepmc   +1 more source

Whole Genome and Single-Cell RNA Sequencing Reveals Clonal Evolution and Heterogeneity of Secondary Plasma Cell Leukemia: A Case Report. [PDF]

EJHaem
Suzuki T, Yokomori R, Sanda T, Ri M, Iida S.   +4 more
europepmc   +1 more source

Single-cell RNA sequencing reveals genes relevant to periodontal therapy and periodontitis. [PDF]

Physiol Genomics
Sekiguchi R, Martin D, Yamada KM.
europepmc   +1 more source

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Single-cell RNA sequencing in pancreatic cancer

Nature Reviews Gastroenterology & Hepatology, 2021
The application of single-cell RNA sequencing platforms has generated notable insights into the heterogeneity underlying pancreatic ductal adenocarcinoma (PDAC), encompassing both the neoplastic compartment and the tumour microenvironment. In this Comment, we discuss the most pertinent findings gleaned from both mouse models and human PDAC samples, as ...
Jincheng Han, Ronald A. DePinho, Anirban Maitra   +2 more
openaire   +2 more sources

Single Cell RNA Sequencing in NASH

2022
Single cell RNA sequencing (scRNA-seq) allows to uncover cellular heterogeneity and the identification of novel subpopulations. In non-alcoholic steatohepatitis (NASH), scRNA-seq is particularly powerful to understand non-parenchymal cell heterogeneity in the liver, e.g. for inflammatory cells.
Jana Hundertmark, Hilmar Berger, Frank Tacke   +2 more
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Introduction to Single‐Cell RNA Sequencing

Current Protocols in Molecular Biology, 2018
AbstractDuring the last decade, high‐throughput sequencing methods have revolutionized the entire field of biology. The opportunity to study entire transcriptomes in great detail using RNA sequencing (RNA‐seq) has fueled many important discoveries and is now a routine method in biomedical research. However, RNA‐seq is typically performed in “bulk,” and
Thale Kristin, Olsen, Ninib, Baryawno
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Single-Cell RNA Sequencing Technologies

2021
All cellular structures are heterogeneous. Thus, investigating true cell heterogeneity is highly required to further understand cellular connectivity and accountability within a disease or normal conditions. Because of its rapidly decreasing costs, the Next-Generation (NGS) sequence is widely used to analyze various biological data.
Manoj Kumar Gupta, Gayatri Gouda, Ravindra Donde, S. Sabarinathan, Piyali Goswami, Goutam Kumar Dash, N. Rajesh, Pallabi Pati, Sushil Kumar Rathode, Ramakrishna Vadde, Lambodar Behera   +10 more
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