Results 251 to 260 of about 10,439,716 (305)

Beyond ACEs and PCEs: Relational Epidemiology and the Childhood Wellness Framework. [PDF]

Children (Basel)
Leason J.
europepmc   +1 more source

SIRT5‐Mediated Desuccinylation of ACAA2 Protects Against Calcium Oxalate‐Induced Kidney Injury by Regulating Fatty Acid Oxidation to Suppress Mitochondrial Oxidative Injury and Ferroptosis

Advanced Science, EarlyView.
The SIRT5/ACAA2 axis maintains lipid metabolic homeostasis in RTECs by promoting ACAA2 desuccinylation and preserving its stability and enzymatic activity, thereby sustaining FAO and limiting PUFA and PUFA‐containing phospholipid accumulation. Under CaOx stress, SIRT5 downregulation impairs FAO, promotes oxidative stress and ferroptosis, and enhances ...
Qinhong Jiang, Caitao Dong, Yuchen Liu, Yuanquan Lou, Wenlong Lin, Sheng Li, Ziqi He   +6 more
wiley   +1 more source

Integrating social identity theory and family systems theory to explain how sociocultural norms become family life. [PDF]

Front Psychol
Mathoora D, Chee KF, Leow S, Woon CO, Ming LC.   +4 more
europepmc   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

Families Flourish: Triangulating Housing, Neighborhood, and Life Coaching for Health. [PDF]

Int J Environ Res Public Health
Reece J, Lee JY, Kleit R.
europepmc   +1 more source

Cavity-dwelling "acorn ants" nest in aborted red pine cones. [PDF]

Ecology
Haan NL, Tolrud EC, Dupuis JR, Gidley B, Grotelueschen A, Hay C, Janevic S, Menon A, Umney S.   +8 more
europepmc   +1 more source

Climate Change as a Chronic Stressor: Biological and Psychological Pathways Linking Environmental Change to Human Well-Being. [PDF]

Life (Basel)
Marano G, Scialpi C, Sottile A, Di Giacomi O, Lanzetta M, Traversi G, Mazza O, Capristo E, Gaetani E, Mazza M.   +9 more
europepmc   +1 more source

Preventive Awareness and Protective Behaviours Toward Vector-Borne Diseases Among Patients at a Tertiary Care Centre in Eastern India: A Cross-Sectional Study. [PDF]

Cureus
Ray B, Kalyani V, Bhowmick T, Panda P, Nazmin S, Boratne A.   +5 more
europepmc   +1 more source

Assets and health across the lifecourse: a framework for supporting migrant populations. [PDF]

J Migr Health
Ettman CK, Galea IT, Abdalla SM.
europepmc   +1 more source

Role of Outpatient Engagement and Medication Adherence in Managing Recurrent Suicidality Amidst Adverse Social Determinants: A Case Series. [PDF]

Cureus
Owasoyo OD, Van Le J, Muzorewa T, Makhani R, Onwuameze O.   +4 more
europepmc   +1 more source