Results 91 to 100 of about 1,313,771 (263)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
RELASI RATING OBLIGASI DAN MARKET INDEKS PASAR MODAL INDONESIA
Jurnal Dinamika Manajemen, 2010 Tujuan dari penelitian ini adalah untuk menguji pengaruh perubahan rating obligasi baik saat di upgrade dan downgrade pada kepekaan hubungan antara return saham dan return pasar.
Amirah -
doaj +1 more source
Understanding Implicit Regularization in Over-Parameterized Single Index Model. [PDF]
J Am Stat Assoc, 2023 Fan J, Yang Z, Yu M.
europepmc +1 more source
Estimation for a partial-linear single-index model
The Annals of Statistics, 2010 In this paper, we study the estimation for a partial-linear single-index model. A two-stage estimation procedure is proposed to estimate the link function for the single index and the parameters in the single index, as well as the parameters in the linear component of the model. Asymptotic normality is established for both parametric components.
Wang, Jane-Ling +3 more
openaire +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A Single Index Model for Longitudinal Outcomes to Optimize Individual Treatment Decision Rules. [PDF]
Stat, 2022 Yao L, Tarpey T.
europepmc +1 more source
Semiparametric models with single-index nuisance parameters [PDF]
Journal of Econometrics, 2014 In many semiparametric models, the parameter of interest is identified through conditional expectations, where the conditioning variable involves a single-index that is estimated in the first step. Among the examples are sample selection models and propensity score matching estimators.
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A single-index model with a surface-link for optimizing individualized dose rules. [PDF]
J Comput Graph Stat, 2022 Park H, Petkova E, Tarpey T, Ogden RT.
europepmc +1 more source
SILVar: Single Index Latent Variable Models
IEEE Transactions on Signal Processing, 2018 Print ISSN: 1053-587X Online ISSN: 1941-0476, IEEE Transactions on Signal Processing, online March 21 ...
Jonathan Mei, José M. F. Moura
openaire +2 more sources