Results 211 to 220 of about 1,326,096 (261)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Development of an opportunistic chest CT-based nomogram for identifying low muscle mass in hospitalized patients with COPD. [PDF]

Front Med (Lausanne)
Gao H, Zou X, Qu Y, Jiao Q, Li H.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Integrated assessment of corrosion behaviour in drinking water distribution systems using experimental analysis, machine learning, and a unified corrosion-scaling index. [PDF]

J Environ Qual
Kumar S, Kumar DR, Singh R, Maurya NS, Wipulanusat W.   +4 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Bayesian Analysis of Postoperative Complication Risk Associated With Preoperative Exposure to Fine Particulate Matter: A Single-Center Cohort Study. [PDF]

Acta Anaesthesiol Scand
Pearson JF, Jacobson CK, Riss CS, Strickland MJ, Lee L, Wan N, Benney TM, Pace NL, Goodrich BK, Gabry JS, Pham JV, Kartchner CK, Wood JA, Andreae MH.   +13 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The MAPK Pathway Coordinates an Immunosuppressive Microenvironment in Colorectal Cancer: A Single-Cell Guided Prognostic Model. [PDF]

Cancer Inform
Zhang Y, Zhang X, Wei J, Wang Y, Shen Y, Jiang A, Liu Q.   +6 more
europepmc   +1 more source

Validity of Center of Pressure Path Length Measured Using a Wii Balance Board for Fall Risk Screening in Community-Dwelling Older Adults. [PDF]

Healthcare (Basel)
Ju MM, Park DS.
europepmc   +1 more source

Integrating Multi-Source and Multi-Temporal UAV Observations to Improve Wheat Yield Prediction Using Machine Learning. [PDF]

Plants (Basel)
Chen C, Liu J, Deng Y, Guo R, Yao W, Yang T, Zhang W, Liu T, Jin X, Xiong W, Li D.   +10 more
europepmc   +1 more source