Results 141 to 150 of about 23,449,692 (250)

The Robustness of Single Index Models in Crop Markets: A Multiple Index Model Test: Reply

Journal of Agricultural and Resource Economics, 1993
Steven C. Blank
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Robustness of Single Index Models in Crop Markets: A Multiple Index Model Test: Comment

Journal of Agricultural and Resource Economics, 1993
Robert A. Collins
doaj   +1 more source

Semiparametric Single-Index Model for Estimating Optimal Individualized Treatment Strategy. [PDF]

Electron J Stat, 2017
Song R, Luo S, Zeng D, Zhang HH, Lu W, Li Z.   +5 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A monotone single index model for spatially referenced multistate current status data. [PDF]

Biometrics
Das S, Chae M, Pati D, Bandyopadhyay D.
europepmc   +1 more source

An Extended Single Index Model with Missing Response at Random

An extended single-index model is considered when responses are missing at random. A three-step estimation procedure is developed to define an estimator for the single index parameter vector by a joint estimating equation. The proposed estimator is shown
Qihua Wang, Tao Zhang, Wolfgang Karl Härdle   +2 more
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Modelling Cumulative Effects of Air Pollution on Respiratory Illnesses by Performing Spline Estimation of Constrained, Additive Single-Index Model. [PDF]

Toxics
Zhang X, Wang S, Shao Q, Wang S, Wei Y.
europepmc   +1 more source