Results 251 to 260 of about 1,476,983 (297)

Machine Learning-Based Multidimensional Oximetry for Obstructive Sleep Apnea Screening: Development and External Validation. [PDF]

JMIR Med Inform
Qian X, Luo H, Ding R, Gao T, Wang H, Wu P, Li N.   +6 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Machine Learning-Based Survival Prediction Models for Young Patients With Gastric Cancer: Model Development and Validation Study. [PDF]

JMIR Cancer
Kang HYJ, Jang W, Ko M, Ryu KS.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Systemic Lupus International Collaborating Clinics Frailty Index predicts mortality in systemic lupus erythematosus patients: data from the Almenara Lupus Cohort. [PDF]

Lupus Sci Med
Rashuamán-Conche BH, Gamboa-Cárdenas RV, Pimentel-Quiroz VR, Singh A, Reátegui-Sokolova C, Elera-Fitzcarrald C, Garcia-Hirsh S, Pastor-Asurza C, Rodríguez-Bellido Z, Perich-Campos RA, Alarcón GS, Ugarte-Gil MF.   +11 more
europepmc   +1 more source

Sex-Specific Associations of Triglyceride-Glucose Index and a Body Shape Index with Cardiometabolic Multimorbidity Risk: A Prospective Cohort Study. [PDF]

J Clin Med
Liu T, Li Y, Huang Y, Pan A, Yin J, Liao Y.   +5 more
europepmc   +1 more source

CTI-related composite adiposity indices and future cardiovascular disease risk among middle-aged and older Chinese adults. [PDF]

Front Nutr
Tang K, Guo X, Lu Y, Li W, Chen H, Chen Z, Wei M.   +6 more
europepmc   +1 more source

A multidimensional biomarker model of vitality and its associations with intrinsic capacity and frailty. [PDF]

J Nutr Health Aging
Chew J, Chia JQ, Lim JP, Yeo A, Tan CN, Chan SP, Lim CL, Lim WS.   +7 more
europepmc   +1 more source

Improving maize LAI estimation by integrating multispectral imagery and digital surface models with ensemble learning. [PDF]

Front Plant Sci
Li W, Lou S, He J, Zhao J, Liu X, Fu G, Pan K, Li T.   +7 more
europepmc   +1 more source