Results 211 to 220 of about 991,877 (258)

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Non-linear relationships between inflammatory indices and erectile dysfunction in a group of young men living with HIV. [PDF]

Basic Clin Androl
Tiecco G, Riva M, Cesanelli F, Rossi L, Colangelo C, Reale SA, Gottardi F, Delbarba A, Cappelli C, Focà E, Castelli F, Quiros-Roldan E.   +11 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Systemic Lupus International Collaborating Clinics Frailty Index predicts mortality in systemic lupus erythematosus patients: data from the Almenara Lupus Cohort. [PDF]

Lupus Sci Med
Rashuamán-Conche BH, Gamboa-Cárdenas RV, Pimentel-Quiroz VR, Singh A, Reátegui-Sokolova C, Elera-Fitzcarrald C, Garcia-Hirsh S, Pastor-Asurza C, Rodríguez-Bellido Z, Perich-Campos RA, Alarcón GS, Ugarte-Gil MF.   +11 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Integrating Lateral Super-Resolution and Axial Progression Reveals Distinct Clathrin Pit Formation Pathways. [PDF]

Traffic
Thompson C, Mondal A, Lafyatis G, Kural C.   +3 more
europepmc   +1 more source

Sex-Specific Associations of Triglyceride-Glucose Index and a Body Shape Index with Cardiometabolic Multimorbidity Risk: A Prospective Cohort Study. [PDF]

J Clin Med
Liu T, Li Y, Huang Y, Pan A, Yin J, Liao Y.   +5 more
europepmc   +1 more source

CTI-related composite adiposity indices and future cardiovascular disease risk among middle-aged and older Chinese adults. [PDF]

Front Nutr
Tang K, Guo X, Lu Y, Li W, Chen H, Chen Z, Wei M.   +6 more
europepmc   +1 more source

A multidimensional biomarker model of vitality and its associations with intrinsic capacity and frailty. [PDF]

J Nutr Health Aging
Chew J, Chia JQ, Lim JP, Yeo A, Tan CN, Chan SP, Lim CL, Lim WS.   +7 more
europepmc   +1 more source