Results 101 to 110 of about 15,189,898 (202)

Extensions of Semiparametric Single Index Models

, 2018
In the recent decades, researchers have made tremendous progress in the study of nonparametric and semiparametric models. Among them, the semiparametric single-index model is intensively studied due to its simplicity and flexibility.
Wang, Cheng
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Deep spatial-spectral fusion of UAV RGB and hyperspectral imagery for potato plant disease detection

International Journal of Applied Earth Observations and Geoinformation
Accurate plant disease detection remains challenging when using single-modality data, which fails to capture comprehensive disease-related features. However, many existing studies rely on pixel-level classification or prior plant segmentation and lack ...
Tianyi Jia, Magdalena Smigaj, Gert Kootstra, Lammert Kooistra   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A perioperative multi-modal fusion and deep learning-based prognostic system for upper tract urothelial carcinoma: a multi-institutional study

Insights into Imaging
Objectives Precise perioperative risk stratification for upper tract urothelial carcinoma (UTUC) is essential. We developed a multimodal prognostic model integrating perioperative clinical data, radiomics, and deep learning (DL) features from baseline CT
Xiang Peng, Yang Li, Wei Shi, Bangxin Xiao, Xiao Xiao, Xiaofeng Yue, Qiao Xv, Qing Jiang, Weiyang He, Yingjie Xv, Mingzhao Xiao   +10 more
doaj   +1 more source

Combining ALS and Satellite Data to Develop High-Resolution Forest Growth Potential Maps for Plantation Stands in Western Canada

Remote Sensing
Mapping forest growth potential across varying environments is challenging, especially when field measurements are limited. In this study, we integrated Airborne Laser Scanning (ALS) terrain derivatives and Sentinel-2 spectral indices to model Site Index
Faezeh Khalifeh Soltanian, Luiz Henrique Terezan, Colin E. Chisholm, Pamela Dykstra, William H. MacKenzie, Che Elkin   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Robust Estimation of L₁-Modal Regression Under Functional Single-Index Models for Practical Applications

Mathematics
We propose a robust procedure to estimate the conditional mode of a univariate outcome O given a Hilbertian explanatory variable I, under the assumption that (O,I) follow a single-index structure.
Fatimah A. Almulhim, Mohammed B. Alamari, Salim Bouzebda, Zoulikha Kaid, Ali Laksaci   +4 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source