Results 111 to 120 of about 15,268,523 (297)

Sparse Single Index Models for Multivariate Responses. [PDF]

open access: yesJ Comput Graph Stat, 2021
Feng Y, Xiao L, Chi EC.
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Generalized Partially Linear Single-Index Models

open access: yes, 1997
The typical generalized linear model for a regression of a response Y on predictors (X, Z) has conditional mean function based on a linear combination of (X, Z).
Gijbels, Irène   +5 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

THE SINGLE INDEX MARKET MODEL IN AGRICULTURE [PDF]

open access: yes
This study illustrates the differences in empirical results due to data measurements and estimating procedures when applying the single index market model in agriculture.
Tambe, A.M.   +3 more
core  

SILVar: Single Index Latent Variable Models

open access: yesIEEE Transactions on Signal Processing, 2018
Print ISSN: 1053-587X Online ISSN: 1941-0476, IEEE Transactions on Signal Processing, online March 21 ...
Jonathan Mei, José M. F. Moura
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Leverage Sampling for Single-Index Models

open access: yes, 2021
In this thesis, a generalized leverage-based sub-sampling method for single-index models is proposed. The approach gives more efficient estimators than random sub-samples of the same size.
Almutairi, Basmah
core  

Large-scale multi-omics enhance risk prediction for type 2 diabetes

open access: yesCardiovascular Diabetology
Background Polygenic risk scores (PRS), metabolomics, and proteomics have each shown promise in improving type 2 diabetes risk prediction, but their combined utility beyond established clinical models remains unclear.
Ruijie Xie   +2 more
doaj   +1 more source

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