Results 161 to 170 of about 15,268,523 (297)

Predictive accuracy of comorbidity index models in assessing mortality risk among hemodialysis patients: A comprehensive single‐center observational cohort study

Aging Medicine
Objectives Comorbidity prediction models have been demonstrated to offer more comprehensive and accurate predictions of death risk compared to single indices.
Yanna Yu, Fen Li, Zhan Wang, Zhibin Ni, Shu Zhang, Weihong Zhao, Xiaohua Pei   +6 more
doaj   +1 more source

Optimizing electrolytic process of anode copper: a mechanism-data dual-driven explainable multi-task deep learning framework

Materials & Design
Complex process parameters and limited accuracy of traditional models lead to difficulties in quality control and low optimization efficiency. Therefore, a high-quality prediction and optimization method for electrolytic copper refining process is ...
Chunmei Liu, Ni Yang, Jianhang Hu, Wuliang Yin, Min Wang, Jianxin Pan, Hua Wang, Kai Yang, Qingtai Xiao   +8 more
doaj   +1 more source

Learning Single Index Models with Diffusion Priors

CoRR
ICML ...
Anqi Tang, Youming Chen, Shuchen Xue, Zhaoqiang Liu   +3 more
openaire   +4 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Large-sample estimation and inference in multivariate single-index models. [PDF]

J Multivar Anal, 2019
Wu J, Peng H, Tu W.
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

A hybrid omnibus test for generalized semiparametric single-index models with high-dimensional covariate sets. [PDF]

Biometrics, 2019
Xu Y, Kim I, Carroll RJ.
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Estimating panel data duration models with censored data [PDF]

, 2005
This paper presents a method for estimating a class of panel data duration models, under which an unknown transformation of the duration variable is linearly related to the observed explanatory variables and the unobserved heterogeneity (or frailty ...
Lee, S.
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