Results 141 to 150 of about 16,585,517 (291)

A family of partial-linear single-index models for analyzing complex environmental exposures with continuous, categorical, time-to-event, and longitudinal health outcomes. [PDF]

Environ Health, 2020
Wang Y, Wu Y, Jacobson MH, Lee M, Jin P, Trasande L, Liu M.   +6 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Modelling illiquid volatility skews [PDF]

, 2014
Includes bibliographical references.Most markets trade liquidly in options on the market index, in fact they often trade at a wide range of strike levels.
Crowther, Servaas Marcus
core   +1 more source

Fine-scale predictive modeling of Aedes mosquito abundance and dengue risk indicators using machine learning algorithms with microclimatic variables

Scientific Reports
Effective prediction of Aedes mosquito abundance and dengue risk indicators such as the Aedes Index (AI) and Dengue Positive Trap Index (DPTI) is essential for early intervention and targeted vector control.
Nazri Che Dom, Nur Athen Mohd Hardy Abdullah, Rahmat Dapari, Siti Aekbal Salleh   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Robustness of Single Index Models in Crop Markets: A Multiple Index Model Test: Reply

Journal of Agricultural and Resource Economics, 1993
Steven C. Blank
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

The Robustness of Single Index Models in Crop Markets: A Multiple Index Model Test: Comment

Journal of Agricultural and Resource Economics, 1993
Robert A. Collins
doaj   +1 more source

Unified Modeling and Multi-Objective Optimization for Disassembly Line Balancing with Distinct Station Configurations

Mathematics
Disassembly line balancing (DLB) is a crucial optimization item in the recycling and remanufacturing of waste products. Considering the variations in the number of operators assigned to each station, this study investigates DLBs with six distinct station
Tao Yin, Yuanzhi Wang, Shixi Cai, Yuxun Zhang, Jianyu Long   +4 more
doaj   +1 more source