Results 251 to 260 of about 15,278,209 (298)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Routine laboratory composite indices and geriatric multisyndrome burden: a head to head evaluation against serum albumin. [PDF]

Front Med (Lausanne)
Erdoğan K, Erten R.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Psychometric evaluation of the Pittsburgh Sleep Quality Index among South African women participating in the Bukhali trial: Healthy Life Trajectories Initiative. [PDF]

J Clin Sleep Med
Alcock S, Beukes J, Hart C, Scheuermaier K, Lye SJ, Norris SA.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Accuracy of machine learning in detecting lymph node metastasis of esophageal cancer: a systematic review and meta-analysis. [PDF]

Transl Cancer Res
Chen J, Weng J, Lin X.
europepmc   +1 more source

Associations of derived inflammatory, lipid, and anthropometric indices with CT-detected pulmonary nodules: a hospital-based cross-sectional study with explainable machine learning. [PDF]

Front Endocrinol (Lausanne)
Wang M, Zhou Y, Wu B, Liu Y, Luo X, Zhang A.   +5 more
europepmc   +1 more source

Blood Count-Derived Inflammatory Indices at Two Timepoints in Insulin-Treated Gestational Diabetes: A Retrospective Cohort Study. [PDF]

Int J Womens Health
Batman A, Konu A, Sabouni T, Özer Çaltek H, Kaya Y, Polat İ.   +5 more
europepmc   +1 more source

Influenza-Like Illness Forecasting Using Multisource Data: Comparative Deep Learning Study. [PDF]

JMIR Med Inform
Dang C, Tong Y, Mo Y, Zhao Z, Li S, Liu F, Jia H, Zhao J, Xu Y, Chen H.   +9 more
europepmc   +1 more source

Baseline and Early On-Treatment Prognostic Nutritional Index in Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer Treated with CDK4/6 Inhibitors. [PDF]

J Clin Med
Çoban E, Kurt AE, Akagündüz F, Demirel A, Tunç MA, Paçacı B, Güren AK, Kocaaslan E, Erel P, Ağyol Y, Çelebi A, Işık S, Demircan NC, Köstek O, Bayoğlu İV, Sarı M.   +15 more
europepmc   +1 more source