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Results 121 to 130 of about 1,058,493 (262)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato +2 more
wiley +1 more source

Predicting spring maize yield using UAV remote sensing

Guan'gai paishui xuebao
【Objective】Predicting potential crop yield is critical not only to policy making but also to improving agricultural management to safeguard food production.
MA Shijiao +5 more
doaj +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

Learning Single Index Models with Diffusion Priors

CoRR
ICML ...
Anqi Tang +3 more
openaire +4 more sources

Predictive accuracy of comorbidity index models in assessing mortality risk among hemodialysis patients: A comprehensive single‐center observational cohort study

Aging Medicine
Objectives Comorbidity prediction models have been demonstrated to offer more comprehensive and accurate predictions of death risk compared to single indices.
Yanna Yu +6 more
doaj +1 more source

Optimizing electrolytic process of anode copper: a mechanism-data dual-driven explainable multi-task deep learning framework

Materials & Design
Complex process parameters and limited accuracy of traditional models lead to difficulties in quality control and low optimization efficiency. Therefore, a high-quality prediction and optimization method for electrolytic copper refining process is ...
Chunmei Liu +8 more
doaj +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source

Large-sample estimation and inference in multivariate single-index models. [PDF]

J Multivar Anal, 2019
Wu J, Peng H, Tu W.
europepmc +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source

single-index model
vegetation index
machine learning