Results 41 to 50 of about 7,631,403 (299)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Dynamic Observation of Ultrashort Pulses with Chaotic Features in a Tm-Doped Fiber Laser with a Single Mode Fiber–Grade Index Multimode Fiber–Single Mode Fiber Structure

open access: yesPhotonics
In this study, we have demonstrated an ultrafast Tm-doped fiber laser utilizing the nonlinear multimode interference (NL-MMI) effect, with a single mode fiber–grade index multimode fiber–single mode fiber (SMF-GIMF-SMF) structure serving as the saturable
Zhenhong Wang   +6 more
doaj   +1 more source

Sensing properties of graphene-oxide-functionalized single-mode–no-core–single-mode fiber structure

open access: yesResults in Physics, 2021
A series of single-mode–no-core–single-mode (SNS) optical fiber sensing structures with different thicknesses of graphene oxide (GO) coating were fabricated and tested with glycerin and magnetic fluid solutions.
Shaokang Yan   +4 more
doaj   +1 more source

Depressed clad hollow optical fiber with fundamental LP01 mode cut-off

open access: yes, 2006
We propose a depressed clad hollow optical fiber with fundamental (LP01) mode cut-off suitable for high power short-wavelength, especially three-level, fiber laser operation by introducing highly wavelength dependent losses at longer wavelengths. The cut-
Codemard, C.   +15 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Efficient large-scale multiplexing of fiber Bragg grating and fiber Fabry-Perot sensors for structural health monitoring applications [PDF]

open access: yes, 2006
Fiber Bragg gratings have been demonstrated as a versatile sensor for structural health monitoring. We present an efficient and cost effective multiplexing method for fiber Bragg grating and fiber Fabry-Perot sensors based on a broadband mode-locked ...
Kirkendall, C. K.   +2 more
core   +4 more sources

Amplified Fiber-Optic Recirculating Delay Lines [PDF]

open access: yes, 1994
Experimental and theoretical results on single- and double-amplified recirculating delay lines are presented. One of our aims is to emphasize their application as filters, showing a wide flexibility of design.
Vizoso, Beatriz   +6 more
core   +3 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Single-mode fiber length for wavefront filtering

open access: yes, 2008
Stellar nulling interferometry offers the possibility of direct imaging of extrasolar planets necessary for the detection of extra-terrestrial life. Achieving optimum performance from the interferometers requires that the wavefronts of light reaching the
Dasgupta, Sonali   +2 more
core   +1 more source

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