Results 71 to 80 of about 435,527 (304)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Wavelength Switchable Mode-Locked Fiber Laser With Tapered Two-Mode Fiber

IEEE Photonics Journal, 2019
We propose and demonstrate a wavelength switchable mode-locked Erbium-doped fiber laser with carbon nanotubes for mode-locking and a tapered two-mode fiber (TTMF) based filter for wavelength selection.
Liqin Xie, Fang Fang, Bing Sun, Mengmeng Chen, Zuxing Zhang   +4 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Real-Time Spatial-Division Multiplexing Transmission with Commercial 400 Gb/s Transponders

Photonics
As single-mode-fiber transmission systems are reaching their capacity limits, spatial-division multiplexing (SDM) techniques have been investigated to increase the per-fiber capacity.
Yuyang Gao, Juhao Li, Yu Tang, Lei Shen, Xian Zhou, Chunxu Zhao, Shikui Shen, Lei Zhang, Xiongyan Tang, Zhangyuan Chen   +9 more
doaj   +1 more source

Movable Fiber-Integrated Hybrid Plasmonic Waveguide on Metal Film

, 2011
A waveguide structure consisting of a tapered nanofiber on a metal film is proposed and analyzed to support highly localized hybrid plasmonic modes. The hybrid plasmonic mode can be efficiently excited through the in-line tapered fiber based on adiabatic
Chen, Xiang-Dong, Cui, Jin-Ming, Dong, Chun-Hua, Guo, Guang-Can, Han, Zheng-Fu, Lv, Liu, Ren, Xi-Feng, Sun, Fang-Wen, Xiao, Yun-Feng, Zou, Chang-Ling   +9 more
core   +1 more source

Complete characterization of ultrashort pulse sources at 1550 nm [PDF]

, 1999
This paper reviews the use of frequency-resolved optical gating (FROG) to characterize mode-locked lasers producing ultrashort pulses suitable for high-capacity optical communications systems at wavelengths around 1550 nm, Second harmonic generation (SHG)
Barry, Liam P., Bollond, Paul G., Dudley, John M., Harvey, John D., Leonhardt, Rainer, Thomsen, Benn C., Thomson, Mark D.   +6 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

High power 405 nm diode laser fiber-coupled single-mode system with high long-term stability [PDF]

, 2013
Fiber-coupled 405 nm diode laser systems are rarely used with fiber output powers higher than 50 mW. A quick degradation of fiber-coupled high power modules with wavelengths in the lower range of the visible spectrum is known for several years. Meanwhile,
Baumann, S., Gonschior, C. P., Grattan, K. T. V., Heyse, D., Klein, K.-F., Sun, T.   +5 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source