Results 161 to 170 of about 7,224,188 (257)

SMITE: Single Molecule Imaging Toolbox Extraordinaire (MATLAB). [PDF]

J Open Source Softw, 2023
Schodt DJ, Wester MJ, Fazel M, Khan S, Mazloom-Farsibaf H, Pallikkuth S, Meddens MBM, Farzam F, Burns EA, Kanagy WK, Rinaldi DA, Jhamba E, Liu S, Relich PK, Olah MJ, Steinberg SL, Lidke KA.   +16 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Single-molecule imaging reveals RNA polymerase II dynamics and TAF1-dependent promoter-proximal pause release. [PDF]

Nat Commun
Haque N, Cutler R, Sidoli S, Coleman RA.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Single-Molecule Imaging and Spectroscopy Enables Quantification of Location-Dependent Light-Matter Interactions on Nanoantennas. [PDF]

Small Sci
Lang L, Nooteboom S, Huijben TAPM, Mahajan S, Marie R, Zijlstra P, Fleischer M.   +6 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Profiling of Integrin Isoforms on Lung-Tropic Exosomes by Spectrally and Kinetically Multiplexed Single-Molecule Imaging. [PDF]

Adv Sci (Weinh)
Liu S, Wang H, Shentu Q, Yuan L, Tie J, Li L, Ai R, Ma B, Qi L, Jiang Y, Fang X.   +10 more
europepmc   +1 more source

Single-molecule imaging in the primary cilium. [PDF]

Methods Cell Biol, 2023
Weiss LE, Love JF, Yoon J, Comerci CJ, Milenkovic L, Kanie T, Jackson PK, Stearns T, Gustavsson AK.   +8 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

4polar3D single molecule imaging of 3D orientation in dense actin networks using ratiometric polarization splitting. [PDF]

Nat Commun
Senthil Kumar CS, Valades Cruz CA, Sison M, Vesga AG, Rey-Barroso J, Curcio V, Alemán-Castañeda LA, Alonso MA, Poincloux R, Mavrakis M, Brasselet S.   +10 more
europepmc   +1 more source