Results 91 to 100 of about 308,465 (261)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Determination of the magnetic anisotropy axes of single-molecule magnets

, 2004
Simple methods are presented allowing the determination of the magnetic anisotropy axes of a crystal of a single-molecule magnet (SMM). These methods are used to determine an upper bound of the easy axis tilts in a standard Mn12-Ac crystal.
G. Christou, G. Christou, M. A. Novak, M. Soler, N. E. Chakov, W. Wernsdorfer, Z. Sun   +6 more
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Single-ion and exchange anisotropy effects and multiferroic behavior in high-symmetry tetramer single molecule magnets

, 2006
We study single-ion and exchange anisotropy effects in equal-spin $s_1$ tetramer single molecule magnets exhibiting $T_d$, $D_{4h}$, $D_{2d}$, $C_{4h}$, $C_{4v}$, or $S_4$ ionic point group symmetry.
A. Bencini, D. Zipse, Dmitri V. Efremov, H. Goldstein, J. D. Jackson, M. Moragues-Cánovas, M. Tinkham, R. A. Klemm, R. Boča, R. S. Rubins, Richard A. Klemm   +10 more
core   +2 more sources

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Tripartite entanglement in mixed-spin triangle trimmer

Condensed Matter Physics
Heisenberg model spin systems offer favourable and manageable physical settings for generating and manipulating entangled quantum states. In this work mixed spin-(1/2,1/2,1) Heisenberg spin trimmer with two different but isotropic Landé g-factors and ...
Zh. Adamyan, V. Ohanyan
doaj   +1 more source

Heisenberg Dimer Single Molecule Magnets in a Strong Magnetic Field

, 2002
We calculate the static and dynamic properties of single crystal, single molecule magnets consisting of equal spin $S=1/2$ or 5/2 dimers. The spins in each dimer interact with each other via the Heisenberg exchange interaction and with the magnetic ...
A. Furrer, A. Lascialfari, A. Lascialfari, A. Zheludev, A.W. Garrett, D. Gatteschi, D. Mentrup, D.A. Tennant, Dmitri V. Efremov, F. Le Gall, G. Müller, H.U. Güdel, H.U. Güdel, H.U. Güdel, J.W. Johnson, M.-H. Julien, R. Caciuffo, R. Klemm, R.A. Klemm, Richard A. Klemm, Y. Furukawa   +20 more
core   +1 more source

Hysteresis Photomodulation via Single-Crystal-to-Single-Crystal Isomerization of a Photochromic Chain of Dysprosium Single-Molecule Magnets.

Journal of the American Chemical Society, 2019
A one-dimensional coordination solid is synthesized by reaction of a bispyridyl dithienylethene (DTE) photochromic unit with the highly anisotropic dysprosium-based single-molecule magnet [Dy(Tppy)F(pyridine)2]PF6.
Maher Hojorat, Hassan Al Sabea, L. Norel, Kévin Bernot, T. Roisnel, F. Gendron, B. L. Guennic, E. Trzop, E. Collet, J. Long, S. Rigaut   +10 more
semanticscholar   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Orientation‐Driven Large Magnetic Hysteresis of Er(III) Cyclooctatetraenide‐Based Single‐Ion Magnets Adsorbed on Ag(100)

Small Science
The molecular self‐assembly and the magnetic properties of two cyclooctatetraenide (COT)‐based single‐ion magnets (SIM) adsorbed on Ag(100) in the sub‐monolayer (ML) range are reported.
Vladyslav Romankov, Moritz Bernhardt, Martin Heinrich, Diana Vaclavkova, Katie Harriman, Niéli Daffé, Bernard Delley, Maciej Damian Korzyński, Matthias Muntwiler, Christophe Copéret, Muralee Murugesu, Frithjof Nolting, Jan Dreiser   +12 more
doaj   +1 more source