Results 71 to 80 of about 308,465 (261)

A four-coordinate cobalt(II) single-ion magnet with coercivity and a very high energy barrier

Nature Communications, 2016
Bistable single-molecule magnets potentially allow information storage at extremely high densities. Here, the authors study an air- and moisture-stable mononuclear tetrahedral cobalt(II) complex, elucidating the origin of its pronounced magnetic ...
Yvonne Rechkemmer, Frauke D. Breitgoff, Margarethe van der Meer, Mihail Atanasov, Michael Hakl, Milan Orlita, Petr Neugebauer, Frank Neese, Biprajit Sarkar, Joris van Slageren   +9 more
doaj   +1 more source

Water-oriented magnetic anisotropy transition

Nature Communications, 2021
Little is known about how the orientation of coordinated water molecules affects the magnetic properties of single molecule magnets. Here the authors combine experimental data and theoretical calculations to study how the rotation of water molecules ...
Sheng-Qun Su, Shu-Qi Wu, Masato Hagihala, Ping Miao, Zhijian Tan, Shuki Torii, Takashi Kamiyama, Tongtong Xiao, Zhenxing Wang, Zhongwen Ouyang, Yuji Miyazaki, Motohiro Nakano, Takumi Nakanishi, Jun-Qiu Li, Shinji Kanegawa, Osamu Sato   +15 more
doaj   +1 more source

Cyclopentadienyl Ligands in Lanthanide Single-Molecule Magnets: One Ring To Rule Them All?

Accounts of Chemical Research, 2018
The discovery of materials capable of storing magnetic information at the level of single molecules and even single atoms has fueled renewed interest in the slow magnetic relaxation properties of single-molecule magnets (SMMs).
Benjamin M. Day, Fu-Sheng Guo, R. Layfield   +2 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Quantum phase interference (Berry phase) in single-molecule magnets of Mn12

, 2001
Magnetization measurements of a molecular clusters Mn12 with a spin ground state of S = 10 show resonance tunneling at avoided energy level crossings. The observed oscillations of the tunnel probability as a function of the magnetic field applied along ...
Aubin, Barnes, Caneschi, Chudnovsky, D. N. Hendrickson, G. Christou, Garg, Garg, Garg, Garg, Garg, Jin, Kececiolu, Landau, Leuenberger, Leuenberger, Liang, Lü, Lü, Lü, M. Soler, Soler, Villain, W. Wernsdorfer, Wernsdorfer, Wernsdorfer, Wernsdorfer, Wernsdorfer, Yoo, Yoo, Zener, Zhang   +31 more
core   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Exploring the magnetic properties of the largest single molecule magnets [PDF]

, 2020
The giant {Mn₇₀} and {Mn₈₄} wheels are the largest nuclearity single-molecule magnets synthesized to date, and understanding their magnetic properties poses a challenge to theory.
Chan, Garnet K.-L., Chen, Dianteng, Cheng, Hai-Ping, O'Rourke, Matthew J., Schurkus, Henry F.   +4 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source