Results 91 to 100 of about 9,699,132 (284)

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

Parent & Family Newsletter, March 2025

open access: yes
Parent and Family Newsletterhttps://ir.library.illinoisstate.edu/pafn/1005/thumbnail ...
Illinois State University, Parent and Family Services
core   +1 more source

Parent & Family Newsletter, February 2025

open access: yes
Parent and Family Newsletterhttps://ir.library.illinoisstate.edu/pafn/1004/thumbnail ...
Illinois State University, Parent and Family Services
core   +1 more source

The influence of left-behind experiences on depression in single-parent adolescents: the mediating role of family satisfaction and the moderating effects of exercise frequency

open access: yesFrontiers in Pediatrics
With the rise of rural-to-urban labor migration, the number of left-behind children in single-parent families has increased, raising concerns about their mental health.
Wang-Cheng Cen   +5 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Parent & Family Newsletter, September 2024

open access: yes
Parent and Family Newsletterhttps://ir.library.illinoisstate.edu/pafn/1000/thumbnail ...
Illinois State University, Parent and Family Services
core   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song   +10 more
wiley   +1 more source

Parent & Family Newsletter, April 2025

open access: yes
Parent and Family Newsletterhttps://ir.library.illinoisstate.edu/pafn/1006/thumbnail ...
Illinois State University, Parent and Family Services
core   +1 more source

Changes in the Structure of Russian Households/Families: a Possible Scenario

open access: yesСтатистика и экономика
Purpose. This article, using data from three Russian population censuses, examines in detail the dynamics of the family structure of the Russian population.
Irina I. Eliseeva, Maria P. Dekina
doaj   +1 more source

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