Results 151 to 160 of about 1,136 (207)

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

open access: yesAdvanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li   +8 more
wiley   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

open access: yesAdvanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li   +14 more
wiley   +1 more source
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Single-Parent Families

1987
With the increase in the number of single-parent families in recent years, the attention paid to this family form has grown considerably—in both the academic and the public media. This increased concern with single-parent families has, however, often manifested itself as a concern about a growing “problem,” a problem that may threaten the American ...
Patricia A. Gongla, Edward H. Thompson
openaire   +1 more source

Single Parent Family

2015
The primary purpose of this study is to determine the psychological, economic, social, legal and cultural effects of becoming a single parent family through death, divorce or separation on the remaining family members. Research has been conducted on how family members have been affected from becoming a single parent family, as well as the development ...
Feyzioğlu, Semiha, Kuşçuoğlu, Ceren
openaire   +1 more source

The single-parent family

Postgraduate Medicine, 1986
Families who have become separated from one of the parents by death or divorce face much stress and adjustment. In addition to carrying the extra burdens of parenting and running a household alone, the single parent may feel isolated from friends and family. Loneliness, depression, and confusion can manifest themselves in various physical and emotional
R, Anstett, B, Lewis
openaire   +2 more sources

Family Support and Child Adjustment in Single-Parent Families

Issues in Comprehensive Pediatric Nursing, 1990
The complex phenomenon of single parenthood is explored within Roy's (Roy & Roberts, 1981) adaptation framework. Correlation analysis of a large family data set supported the literature and the conceptual framework. Findings suggested that single parents experienced a characteristic set of stressors distinguishing them from two-parent families.
M L, Friedemann, M, Andrews
openaire   +2 more sources

A Structural Approach to the Single‐Parent Family

Family Process, 1982
Although the single‐parent family is becoming a predominant family structure, there is a surprising scarcity of articles discussing its typical problems or detailing specific therapeutic approaches. This paper attempts, first, to list some core problems encountered by all single parents and, second, to present a sequence of therapeutic approaches ...
openaire   +2 more sources

The Single‐Parent Family: An Author's Reflection

Family Process, 1984
In view of the dramatic rise in the divorce rate, this paper proposes that separation and divorce be viewed as normal phases of the family life cycle and be reframed in positive terms, such as a couple “being ready for a new relationship” or children “being the lucky possessors of two families instead of one.” It further makes a plea for more extensive
openaire   +2 more sources

Single-Parent Families

Nursing Clinics of North America, 1977
J A, Horowitz, B J, Perdue
openaire   +2 more sources

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