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Single-particle imaging for biosensor applications

Emerging Imaging and Sensing Technologies for Security and Defence II, 2017
Current state-of-the-art technology for in-vitro diagnostics employ laboratory tests such as ELISA that consists of a multi-step test procedure and give results in analog format. Results of these tests are interpreted by the color change in a set of diluted samples in a multi-well plate.
Celalettin Yurdakul   +6 more
openaire   +1 more source

Ultrahigh-Throughput Single-Particle Hyperspectral Imaging of Gold Nanoparticles

Analytical Chemistry, 2023
Gold nanoparticles (AuNPs) have become increasingly useful in recent years for their roles in nanomedicine, cellular biology, energy storage and conversion, photocatalysis, and more. At the single-particle level, AuNPs have heterogeneous physical and chemical properties which are not resolvable in ensemble measurements.
James Ethan Batey   +3 more
openaire   +2 more sources

Single-particle tracking image microscopy.

Methods in enzymology, 2003
The techniques of single particle tracking (SPT) and optical force microscopy (OFM) as described above allow direct imaging of the motion of molecules in the membrane of live cells, and provide a means of controlling the movement by an almost noninvasive method.
Ken, Ritchie, Akihiro, Kusumi
openaire   +1 more source

Single-particle imaging

2007
The current status of single-particle X-ray imaging - or "X-ray crystallography without need for a crystal" - is reviewed, with particular emphasis on the Stony Brook/Cornell/Berkeley single yeast cell imaging project. Two-dimensional (2D) images of a quick-frozen yeast cell have been obtained with a resolution which, if carried out in three ...
openaire   +1 more source

Diffractive Imaging of Single Particles

2019
The computational methods and applications of diffractive (lensless) imaging are reviewed. Far-field scattering (e. g., by neutrons, electrons, light, or x-rays) by a nonperiodic localized potential is detected and the phase problem solved using iterative optimization methods, which allows a three-dimensional image of the object potential to be ...
openaire   +1 more source

Brightness calibrates particle size in single particle fluorescence imaging

Optics Letters, 2015
This Letter provides a novel approach to quantify the particle sizes of highly bright semiconductor polymer dots (Pdots) for single-particle imaging and photobleaching studies. A quadratic dependence of single-particle brightness on particle size was determined by single-particle fluorescence imaging and intensity statistics.
Zhihe, Liu   +5 more
openaire   +2 more sources

Lanthanide‐Doped Upconversion Nanoparticles for Single‐Particle Imaging

ChemBioChem
Lanthanide‐doped upconversion nanoparticles (UCNPs) have recently demonstrated great promise in single‐particle imaging (SPI) due to their exceptional photostability and minimal background fluorescence. However, their limited brightness has posed a significant barrier to wider adoption in SPI applications.
Huan Ling   +4 more
openaire   +2 more sources

Molecular imaging in oncology: Current impact and future directions

Ca-A Cancer Journal for Clinicians, 2022
Steven P Rowe, Martin G Pomper
exaly  

[27] Single-particle tracking image microscopy

2003
Ken Ritchie, Akihiro Kusumi
openaire   +1 more source

Functional Imaging of Cancer with Emphasis on Molecular Techniques

Ca-A Cancer Journal for Clinicians, 2007
Mohamed Houseni, Abass Alavi
exaly  

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